Adagene Inc., a clinical stage biotechnology company, engages in the research, development, and production of monoclonal antibody drugs for cancers in the People's Republic of China. Its lead product candidate is the ADG126, a masked fully-human anti-CTLA-4 mAb which is in phase 1b/2 clinical development for the treatment of cancer. The company also develops ADG116, a fully human anti-CTLA-4 antibody generated using NEObody technology, which is in phase 1b/2 clinical trials to treat advanced/metastatic solid tumors; ADG206, which is in phase 1 clinical development to treat advanced metastatic solid tumors; ADG104, anti-PD-L1 monoclonal antibody which is in phase 2 clinical development; and ADG125, a novel anti-CSF-1R mAb which is in Phase 2 clinical development. In addition, it is developing ADG138, a HER2xCD3 POWERbody which is in pre clinical trial to treat low expressing tumors, as well as resistant/refractory tumors; ADG152, a CD20xCD3 POWERbody which is in preclincal trial to treat off-tumor toxicities; ADG153, a masked anti-CD47 IgG1 SAFEbody, wihx is in preclinical trial for the treatment of hematologic and solid tumor; and CD28 T-cell engagers, an anti-CD28 bispecific POWERbody TCEs to treat solid tumors. The company was incorporated in 2011 and is headquartered in Suzhou, China. Show more

Building C14, Xinghu Street, Suzhou Industrial Park, Suzhou, 215123, China

Biotechnology
Healthcare

Market Cap

184.8M

52 Wk Range

$1.30 - $4.58

Previous Close

$3.92

Open

$3.87

Volume

6,491

Day Range

$3.87 - $3.87

Enterprise Value

115.1M

Cash

62.83M

Avg Qtr Burn

N/A

Insider Ownership

15.51%

Institutional Own.

28.63%

Qtr Updated


Only showing assets and stage. See catalyst data with a free or premium account. Unlock more data with a free account.

Drug & IndicationStage & EventCatalyst Date

Phase 2

Data readout

Muzastotug (ADG126) (Masked CTLA-4 Antibody) Details
Unresectable Locally Advanced Or Metastatic Hepatocellular Carcinoma

Phase 1/2

Data readout

Phase 1/2

Data readout

Phase 1/2

Data readout

ADG116 (CTLA4) Details
Solid tumor/s, Cancer

Phase 1/2

Update

ADG106 (CD137) Details
Solid tumor/s, Cancer, Non-small cell lung carcinoma, Breast cancer, ER+/HER2- breast cancer

Failed

Discontinued