Adaptimmune Therapeutics plc, a commercial-stage biopharmaceutical company, provides novel cell therapies primarily to cancer patients in the United States and the United Kingdom. It develops TECELRA ((famitresgene autoleucel or afami-cel), a genetically modified autologous T-cell immunotherapy for the treatment of adults with unresectable or metastatic synovial sarcoma; Lete-cel for the treatment synovial sarcoma and myxoid liposarcoma; and ADP-5701, which is in Phase 1 clinical trial for the treatment of head and neck cancer. The company also focuses on the development of T-cell therapies directed to PRAME (ADP-600) and CD70 (ADP-520). It has strategic collaboration with Galapagos to clinical proof-of-concept trial to evaluate the safety and efficacy of uza-cel produced on Galapagos' decentralized manufacturing platform (ADP-5701) in patients with head and neck cancer; collaboration and license agreement with Noile-Immune Biotech, Inc. and strategic alliance agreement with the MD Anderson Cancer Center. Adaptimmune Therapeutics plc was founded in 2008 and is headquartered in Abingdon, the United Kingdom. Show more

Location: 60 Jubilee Avenue, Abingdon, OX14 4RX, United Kingdom | Website: https://www.adaptimmune.com | Industry: Biotechnology | Sector: Healthcare


Market Cap

64.94M

52 Wk Range

$0.20 - $1.48

Previous Close

$0.24

Open

$0.24

Volume

557,185

Day Range

$0.24 - $0.25

Enterprise Value

378.8M

Cash

59.56M

Avg Qtr Burn

-26.96M

Insider Ownership

0.63%

Institutional Own.

44.16%

Qtr Updated

03/31/25


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date

Approved

Quarterly sales

Lete-cel (NY-ESO) Details
Myxoid/Round cell liposarcoma, Sarcoma

BLA

Submission

Uzatresgene autoleucel (uza-cel)(ADP-A2M4CD8) (MAGE A4) +/- nivolumab Details
Head and neck cancer, Bladder cancer, Cancer, Solid tumor/s, Urothelial cancer

Failed

Discontinued

afami-cel (afamitresgene autoleucel) (ADP-A2M4) + pembro Details
Head and neck cancer, Homozygous familial hypercholesterolemia, Cancer, Solid tumor/s

Failed

Discontinued

TC-110 (CD19) Details
Non-Hodgkin lymphoma, Leukemia, Acute lymphoblastic leukemia, Diffuse large B cell lymphoma, Cancer

Failed

Discontinued

ADP-A2AFP Details
Hepatocellular carcinoma, Cancer

Failed

Discontinued

Gavo-cel (TC-210) (Mesothelin) + nivolumab Details
Solid tumor/s, Ovarian cancer, Cancer

Failed

Discontinued

TC-510 Details
Cancer, Colorectal cancer , Ovarian cancer, Mesothelioma, Triple-negative breast cancer , Pancreatic cancer

Failed

Discontinued

Failed

Discontinued