ADCT - ADC Therapeutics

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ADC Therapeutics NEW YORK STOCK EXCHANGE INC.:ADCT ADC Therapeutics SA is a late clinical-stage oncology-focused biotechnology company pioneering the development and commercialization of potent and targeted antibody drug conjugates (ADCs) for patients with hematological malignancies and solid tumors. The Company has created a deep clinical pipeline by combining its decades of experience and strategic target selection with proprietary next-generation pyrrolobenzodiazepine (PBD) technology. The Company's Biologics License Application for its lead product candidate, loncastuximab tesirine (Lonca, formerly ADCT-402) for the treatment of relapsed or refractory diffuse large B-cell lymphoma was given priority review status by the U.S. Food and Drug Administration and a Prescription Drug User Fee Act (PDUFA) target date of May 21, 2021. The Company's second lead product candidate, camidanlumab tesirine (Cami, formerly ADCT-301), is being evaluated in a 117-patient pivotal Phase 2 clinical trial for the treatment of relapsed or refractory Hodgkin lymphoma.

Location: | Website: adctherapeutics.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing


Market Cap

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52 Wk Range

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Previous Close

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Avg Volume

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Enterprise Value

371.6M

Cash

274.3M

Avg Qtr Burn

-33.4M

Short % of Float

4.11%

Insider Ownership

21.03%

Institutional Own.

61.40%

Qtr Updated

09/30/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
ZYNLONTA (Loncastuximab Tesirine) (CD19) Details
Follicular lymphoma, Mantle cell lymphoma, Diffuse large B cell lymphoma

Approved

Update

Camidanlumab Tesirine (CD25) Details
Solid tumor/s, Cancer, Hodgkin Lymphoma

BLA

Submission

Phase 3

Data readout

ZYNLONTA (Loncastuximab Tesirine) (CD19) Details
Cancer, Blood cancer, Marginal zone lymphoma

Phase 2

Data readout

ZYNLONTA + Rituximab Details
Blood cancer, Follicular lymphoma

Phase 2

Data readout

ZYNLONTA (Loncastuximab Tesirine) (CD19) Details
Cancer, Blood cancer, Diffuse large B cell lymphoma

Phase 2

Update

ZYNLONTA (Loncastuximab Tesirine) (CD19) Details
Non-Hodgkin lymphoma, Blood cancer, Cancer

Phase 1b

Data readout

ADCT-602 (CD22) Details
Acute lymphoblastic leukemia

Phase 1a

Data readout

ZYNLONTA (Loncastuximab Tesirine) (CD19) Details
Cancer, Diffuse large B cell lymphoma

Failed

Discontinued

Failed

Discontinued

Failed

Discontinued