Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes used for the treatment of hemolytic anemias in adults with PK deficiency. The company's PYRUKYND product also used for the treatment of sickle cell disease that is in phase 3 clinical trial; for the treatment of PK deficiency in pediatric patients; and for the treatment of adult patients with non-transfusion dependent and transfusion-dependent alpha- or beta-thalassemia. In addition, it develops tebapivat, a PK activator for the treatment of lower-risk myelodysplastic syndrome and hemolytic anemias; AG-181, a phenylalanine hydroxylase stabilizer for the treatment of phenylketonuria (PKU); and AG-236, an siRNA in-licensed from Alnylam, targeting the transmembrane serine protease 6 (TMPRSS6) gene for the treatment of polycythemia vera. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts. Show more
Location: 88 Sidney Street, Cambridge, MA, 02139, United States | Website: https://www.agios.com | Industry: Biotechnology | Sector: Healthcare
Market Cap
2.038B
52 Wk Range
$23.42 - $62.58
Previous Close
$35.08
Open
$35.38
Volume
384,278
Day Range
$35.11 - $36.16
Enterprise Value
1.148B
Cash
938.9M
Avg Qtr Burn
-101.5M
Insider Ownership
1.66%
Institutional Own.
-
Qtr Updated
06/30/25
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
VORANIGO (Vorasidenib) Details Glioma, Brain tumor | Approved Quarterly sales | |
Tibsovo (Ivosidenib) (IDH1m inhibitor) Details AML (Acute Myeloid Leukemia) | Approved Quarterly sales | |
PYRUKYND (Mitapivat) (pyruvate kinase R (PKR) activator) Details Sickle cell disease, Anemia | Approved Quarterly sales | |
PYRUKYND (Mitapivat) Details Beta thalessemia | PDUFA Approval decision | |
PYRUKYND (Mitapivat) (pyruvate kinase R (PKR) activator) Details Pyruvate Kinase Deficiency | NDA Submission | |
PYRUKYND (Mitapivat) (pyruvate kinase R (PKR) activator) Details Sickle cell disease, Anemia Suspected Mover™ Susp. Mover™ | Phase 3 Data readout | |
Tebapivat (AG-946) Details Myelodysplastic syndrome | Phase 2b Update | |
Tebapivat Details Sickle cell disease, Blood disorder | Phase 2 Initiation | |
AG-181 Details Phenylketonuria | Phase 1 Data readout | |
AG-236 Details Polycythemia vera | IND Submission |