Allogene Therapeutics, Inc. a clinical stage immuno-oncology company, develops and commercializes genetically engineered allogeneic T cell therapies for the treatment of cancer and autoimmune diseases. It develops, manufactures, and commercializes UCART19, an allogeneic anti-CD19 chimeric antigen receptor (CAR) T cell product candidate for the treatment of patients with R/R CD19 positive B-cell acute lymphoblastic leukemia (ALL). The company also develops cemacabtagene ansegedleucel, an engineered allogeneic CAR T cell product candidate that targets CD19 for the treatment of large B-cell lymphoma. In addition, it provides clinical-stage products, such as ALLO-501, cema-cel, ALLO-316, ALLO-329, ALLO-715, and ALLO-605; DLL3 for the treatment of small cell lung cancer; Claudin 18.2 for the treatment of gastric and pancreatic cancer; and FLT3 for the treatment of acute myeloid leukemia. The company has license and collaboration agreements with Pfizer Inc., Servier, Cellectis S.A., and Notch Therapeutics Inc. It also has a strategic collaboration agreement with The University of Texas MD Anderson Cancer Center for the preclinical and clinical investigation of allogeneic CAR T cell product candidates; and a strategic partnership with Foresight Diagnostics to develop MRD-based In-Vitro Diagnostic for use in ALPHA3. The company was incorporated in 2017 and is headquartered in South San Francisco, California. Show more
210 East Grand Avenue, South San Francisco, CA, 94080, United States
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Market Cap
467.4M
52 Wk Range
$0.86 - $2.32
Previous Close
$2.05
Open
$2.06
Volume
4,397,229
Day Range
$2.01 - $2.15
Enterprise Value
92.35M
Cash
252.2M
Avg Qtr Burn
-29.69M
Insider Ownership
16.63%
Institutional Own.
65.32%
Qtr Updated
09/30/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Cemacabtagene Ansegedleucel (cema-cel) Details Cancer, Diffuse large B cell lymphoma | Phase 2 Data readout | |
ALLO-647 (Anti-CD52 mAb) Details Cancer, Diffuse large B cell lymphoma | Phase 2 Update | |
ALLO-329 [CD19/CD70 Dual CAR] Details Autoimmune disease | Phase 1 Data readout | |
Cemacabtagene ansegedleucel, or cema-cel [ALLO-501A (CD19)] Details Cancer, Chronic lymphocytic leukemia | Phase 1 Update | |
ALLO-715 (BCMA) Details Cancer, Multiple myeloma | Phase 1 Update | |
ALLO-605 (BCMA) Details Multiple myeloma, Cancer | Phase 1 Update | |
ALLO-316 (CD70) Details Clear cell renal cell carcinoma (ccRCC) | Phase 1 Update |
