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Aprea Therapeutics NasdaqCM:APRE Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing novel synthetic lethality-based cancer therapeutics that targets DNA damage response pathways. Its lead product candidates are APR-1051, an orally bioavailable small-molecule inhibitor of WEE1 kinase that is in Phase 1 clinical trial for the treatment of patients with advanced solid tumors with biomarkers; and ATRN-119, an ATR inhibitor, which is in Phase 1/2a clinical trial for solid tumor indications. The company is headquartered in Doylestown, Pennsylvania.
Location: 3805 Old Easton Road, Doylestown, PA, 18902, United States | Website: https://aprea.com | Industry: Biotechnology | Sector: Healthcare
Market Cap
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52 Wk Range
$ - $
Previous Close
$N/A
Open
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Day Range
N/A - N/A
Volume
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Avg Volume
N/A
Enterprise Value
-7.981M
Cash
19.28M
Avg Qtr Burn
-3.313M
Short % of Float
1.70%
Insider Ownership
11.75%
Institutional Own.
40.94%
Qtr Updated
03/31/25
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
ATRN-119 Details Solid tumor/s, Cancer | Phase 1/2 Data readout | |
APR-1051 Details Solid tumor/s, Cancer | Phase 1 Data readout | |
Eprenetapopt (APR-246) + azacitidine Details Acute myeloid leukemia, Cancer, Myelodysplastic syndrome | Failed Discontinued | |
APR-548 + azacitidine Details Mutant Myelodysplastic Syndromes | Failed Discontinued | |
Eprenetapopt (APR-246) + Azacitidine Details Blood disorder, Myelodysplastic syndrome | Failed Discontinued |