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Aptevo Therapeutics NasdaqCM:APVO Aptevo Therapeutics Inc., a clinical-stage research and development biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company develops its products using ADAPTIR and ADAPTIR-FLEX platforms to generate monospecific, bispecific, and multi-specific antibody candidates capable of enhancing the human immune system against cancer cells. Its lead clinical blood cancer candidate is mipletamig that is in Phase 1b/2 clinical trial for the treatment of acute myelogenous leukemia. The company also develops ALG.APV-527, a novel investigational bispecific ADAPTIR candidate that is in Phase 1 clinical trial for the treatment of non-small cell lung cancer, head and neck, colorectal, pancreatic, breast, and other solid tumors; APVO603, a preclinical dual agonist bispecific ADAPTIR candidate to treat multiple solid tumors; APVO442, a preclinical bispecific candidate based on the ADAPTIR-FLEX platform technology for the treatment of multiple solid tumors; and APVO711, a preclinical dual mechanism bispecific ADAPTIR candidate to treat prostate cancer. It has a collaboration and option agreement with Alligator Bioscience AB to develop ALG.APV-527. Aptevo Therapeutics Inc. was incorporated in 2016 and is headquartered in Seattle, Washington.

Location: 2401 4th Avenue, Seattle, WA, 98121, United States | Website: https://aptevotherapeutics.com | Industry: Biotechnology | Sector: Healthcare

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52 Wk Range

$ - $

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Avg Volume

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Enterprise Value

4.189M

Cash

2.139M

Avg Qtr Burn

-5.927M

Short % of Float

5.16%

Insider Ownership

3.11%

Institutional Own.

3.31%

Qtr Updated

03/31/25

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Drug & Indication	Stage & Event	Catalyst Date
APVO436 (mipletamig) +/- Venetoclax + Azacitidine Details Myelodysplastic syndrome, Acute myeloid leukemia, Cancer	Phase 1/2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
ALG.APV-527 (4-1BB x 5T4) Details Cancer, Solid tumor/s, Colorectal cancer , Pancreatic cancer, Non-small cell lung carcinoma, Breast cancer	Phase 1 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.