ARAV - Aravive Inc

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Aravive Inc NASDAQ:ARAV Aravive, Inc. is a clinical-stage oncology company developing transformative therapeutics designed to halt the progression of life-threatening diseases. Aravive is based in Houston, Texas and received a Product Development Award from the Cancer Prevention & Research Institute of Texas (CPRIT) in 2016. Aravive's lead product candidate, AVB-500, is an ultra-high affinity decoy protein that targets the GAS6-AXL signaling pathway associated with tumor cell growth. Aravive successfully completed a Phase 1b trial of AVB-500 in platinum resistant ovarian cancer and has initiated a registrational Phase 3 trial of AVB-500 at a dose of 15 mg/kg. While the Phase 1b trial of AVB-500 in platinum resistant ovarian cancer was a safety trial and not powered to demonstrate efficacy, all 5 patients in the 15 mg/kg cohort experienced clinical benefit, with 1 complete response, 2 partial responses, and 2 stable disease. The Company is dosing patients in its Phase 1b/2 trial in clear cell renal cell carcinoma.

Location: River Oaks Tower, 3730 Kirby Drive, Suite 1200, Texas, 77098, US | Website: aravive.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing


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Short % of Float

2.95%

Insider Ownership

38.69%

Institutional Own.

8.21%

Qtr Updated

09/30/23


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