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Aravive Inc NASDAQ:ARAV Aravive, Inc. is a clinical-stage oncology company developing transformative therapeutics designed to halt the progression of life-threatening diseases. Aravive is based in Houston, Texas and received a Product Development Award from the Cancer Prevention & Research Institute of Texas (CPRIT) in 2016. Aravive's lead product candidate, AVB-500, is an ultra-high affinity decoy protein that targets the GAS6-AXL signaling pathway associated with tumor cell growth. Aravive successfully completed a Phase 1b trial of AVB-500 in platinum resistant ovarian cancer and has initiated a registrational Phase 3 trial of AVB-500 at a dose of 15 mg/kg. While the Phase 1b trial of AVB-500 in platinum resistant ovarian cancer was a safety trial and not powered to demonstrate efficacy, all 5 patients in the 15 mg/kg cohort experienced clinical benefit, with 1 complete response, 2 partial responses, and 2 stable disease. The Company is dosing patients in its Phase 1b/2 trial in clear cell renal cell carcinoma.
Location: River Oaks Tower, 3730 Kirby Drive, Suite 1200, Texas, 77098, US | Website: aravive.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing
Market Cap
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52 Wk Range
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Avg Qtr Burn
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Short % of Float
2.95%
Insider Ownership
38.69%
Institutional Own.
8.21%
Qtr Updated
09/30/23
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Batiraxcept (AVB-500) Details Renal cell carcinoma | Phase 3 Initiation | |
Batiraxcept (AVB-500) Details Pancreatic cancer | Failed Discontinued | |
Batiraxcept (AVB-500) Details Solid tumor/s, Cancer, Ovarian cancer | Failed Discontinued | |
Batiraxcept (AVB-500) Details Solid tumor/s, Cancer, Renal cell carcinoma | Failed Discontinued |