Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. Its pipeline includes Plozasiran to reduce production of apolipoprotein C-III in Phase 3 studies; Zodasiran to reduce production of angiopoietin-like protein 3 in Phase 3 clinical trials; ARO-DIMER-PA, a dual functional RNAi molecule in a Phase 1/2a clinical trials; and ARO-PNPLA3, an investigational RNAi therapeutic in Phase 1 clinical trials. The company also develops ARO-INHBE, to reduce the hepatic expression of the INHBE gene and its secreted gene product, Activin E in Phase 1/2a clinical trials; ARO-ALK7 to silence adipocyte expression of the ACVR1C gene in Phase 1/2a clinical trials; ARO-RAGE to reduce production of the receptor for advanced glycation end products in Phase 1/2a clinical trials; and ARO-MAPT, an investigational RNAi-based therapy. In addition, it is developing ARO-C3 to reduce production of C3 in Phase 1/2a clinical trials; and ARO-CFB to reduce hepatic expression of CFB in a Phase 1/2a clinical trials. The company has collaboration and license Agreements with Glaxosmithkline Intellectual Property (No. 3) Limited; Takeda Pharmaceutical Company Limited; Amgen Inc.; and Sarepta Therapeutics, Inc. Arrowhead Pharmaceuticals, Inc. was founded in 2003 and is headquartered in Pasadena, California. Show more

177 East Colorado Boulevard, Suite 700, Pasadena, CA, 91105, United States

Biotechnology
Healthcare
Start AI Chat

Market Cap

8.842B

52 Wk Range

$9.57 - $76.76

Previous Close

$63.14

Open

$63.43

Volume

413,387

Day Range

$62.57 - $64.55

Enterprise Value

8.568B

Cash

916.6M

Avg Qtr Burn

N/A

Insider Ownership

3.83%

Institutional Own.

84.28%

Qtr Updated

12/31/25


Only showing assets and stage. See catalyst data with a free or premium account. Unlock more data with a free account.

Drug & IndicationStage & EventCatalyst Date
REDEMPLO® (plozasiran) Details
Familial chylomicronemia syndrome (FCS)

Approved

Quarterly sales

Zodasiran (ARO-ANG3) Details
Homozygous Familial Hypercholesterolemia

Phase 3

Data readout

Plozasiran (ARO-APOC3) Details
Severe hypertriglyceridemia

Phase 3

Data readout

Fazirsiran (ARO-AAT) (TAK-999) Details
Severe alpha-1 antitrypsin deficiency, Liver disease

Phase 3

Update

Phase 3

Initiation

ARO-ANG3 Details
Dyslipidemia

Phase 2

Update

ARO-DM1 Details
Myotonic Dystrophy Type 1

Phase 1/2

Data readout

ARO-CFB Details
Complement mediated diseases, Kidney disease, IgA nephropathy

Phase 1/2

Data readout

ARO-INHBE Details
Obesity, Metabolic disorder

Phase 1/2

Data readout

ARO-MAPT Details
Tauopathies including Alzheimer’s disease

Phase 1/2

Data readout

Phase 1/2

Data readout

ARO-MUC5AC Details
Lung disease, Muco-Obstructive Lung Diseases

Phase 1/2

Data readout

ARO-MMP7 Details
Idiopathic pulmonary fibrosis

Phase 1/2

Data readout

ARO-C3 (RNAi) Details
Paroxysmal nocturnal hemoglobinuria , Renal disease, IgA nephropathy, C3 Glomerulopathy

Phase 1/2

Update

ARO-RAGE Details
Muco-Obstructive Lung Diseases, Inflammatory disease, Asthma

Phase 1/2

Update

ARO-DIMER-PA (RNAi Therapeutic) Details
Atherosclerotic Cardiovascular Disease Due To Mixed Hyperlipidemia

Phase 1/2

Initiation

ARO-DUX4 Details
Facioscapulohumeral muscular dystrophy

Phase 1/2

Initiation

Failed

Discontinued

ARO-HSD Details
Liver disease, Non-alcoholic steatohepatitis

Failed

Discontinued