Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. Its pipeline includes Plozasiran to reduce production of apolipoprotein C-III in Phase 3 studies; Zodasiran to reduce production of angiopoietin-like protein 3 in Phase 3 clinical trials; ARO-DIMER-PA, a dual functional RNAi molecule in a Phase 1/2a clinical trials; and ARO-PNPLA3, an investigational RNAi therapeutic in Phase 1 clinical trials. The company also develops ARO-INHBE, to reduce the hepatic expression of the INHBE gene and its secreted gene product, Activin E in Phase 1/2a clinical trials; ARO-ALK7 to silence adipocyte expression of the ACVR1C gene in Phase 1/2a clinical trials; ARO-RAGE to reduce production of the receptor for advanced glycation end products in Phase 1/2a clinical trials; and ARO-MAPT, an investigational RNAi-based therapy. In addition, it is developing ARO-C3 to reduce production of C3 in Phase 1/2a clinical trials; and ARO-CFB to reduce hepatic expression of CFB in a Phase 1/2a clinical trials. The company has collaboration and license Agreements with Glaxosmithkline Intellectual Property (No. 3) Limited; Takeda Pharmaceutical Company Limited; Amgen Inc.; and Sarepta Therapeutics, Inc. Arrowhead Pharmaceuticals, Inc. was founded in 2003 and is headquartered in Pasadena, California. Show more
177 East Colorado Boulevard, Suite 700, Pasadena, CA, 91105, United States
Market Cap
8.842B
52 Wk Range
$9.57 - $76.76
Previous Close
$63.14
Open
$63.43
Volume
413,387
Day Range
$62.57 - $64.55
Enterprise Value
8.568B
Cash
916.6M
Avg Qtr Burn
N/A
Insider Ownership
3.83%
Institutional Own.
84.28%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
REDEMPLO® (plozasiran) Details Familial chylomicronemia syndrome (FCS) | Approved Quarterly sales | |
Zodasiran (ARO-ANG3) Details Homozygous Familial Hypercholesterolemia | Phase 3 Data readout | |
Plozasiran (ARO-APOC3) Details Severe hypertriglyceridemia | Phase 3 Data readout | |
Fazirsiran (ARO-AAT) (TAK-999) Details Severe alpha-1 antitrypsin deficiency, Liver disease | Phase 3 Update | |
Plozasiran (ARO-APOC3) Details Dyslipidemia | Phase 3 Initiation | |
ARO-ANG3 Details Dyslipidemia | Phase 2 Update | |
ARO-DM1 Details Myotonic Dystrophy Type 1 | Phase 1/2 Data readout | |
ARO-CFB Details Complement mediated diseases, Kidney disease, IgA nephropathy | Phase 1/2 Data readout | |
ARO-INHBE Details Obesity, Metabolic disorder | Phase 1/2 Data readout | |
ARO-MAPT Details Tauopathies including Alzheimer’s disease | Phase 1/2 Data readout | |
ARO-ALK7 Details Obesity | Phase 1/2 Data readout | |
ARO-MUC5AC Details Lung disease, Muco-Obstructive Lung Diseases | Phase 1/2 Data readout | |
ARO-MMP7 Details Idiopathic pulmonary fibrosis | Phase 1/2 Data readout | |
ARO-C3 (RNAi) Details Paroxysmal nocturnal hemoglobinuria , Renal disease, IgA nephropathy, C3 Glomerulopathy | Phase 1/2 Update | |
ARO-RAGE Details Muco-Obstructive Lung Diseases, Inflammatory disease, Asthma | Phase 1/2 Update | |
ARO-DIMER-PA (RNAi Therapeutic) Details Atherosclerotic Cardiovascular Disease Due To Mixed Hyperlipidemia | Phase 1/2 Initiation | |
ARO-DUX4 Details Facioscapulohumeral muscular dystrophy | Phase 1/2 Initiation | |
JNJ-3989 (ARO-HBV) Details Hepatitis B | Failed Discontinued | |
ARO-HSD Details Liver disease, Non-alcoholic steatohepatitis | Failed Discontinued |
