Autolus Therapeutics plc, a clinical-stage biopharmaceutical company, develops T cell therapies for the treatment of cancer and autoimmune diseases in the United Kingdom and internationally. The company offers AUCATZYL, a gene therapy product consisting of autologous T cells that are transduced with a lentiviral vector to express a novel anti-CD19 chimeric antigen receptor. It also develops obe-cel, which is in phase 1 to treat systemic lupus erythematosus, progressive multiple sclerosis, B-NHL and CLL, and CNS lymphoma; obe-cel, which is in phase 2 to treat pediatric B-ALL and lupus nephritis; AUTO1/22 to treat pediatric B-ALL, which is phase 1; AUTO8, which is in phase 1 to treat multiple myeloma and light chain amyloidosis; AUTO4/5, which is in preclinical stage to treat peripheral TCL; AUTO6NG, which is in phase 1 to treat neuroblastoma; and AUTO9, which is in preclinical stage to treat acute myeloid leukemia. The company was incorporated in 2014 and is headquartered in London, the United Kingdom. Show more

The Mediaworks, White City, London, W12 7FP, United Kingdom

Biotechnology
Healthcare

Market Cap

391.2M

52 Wk Range

$1.15 - $2.70

Previous Close

$1.41

Open

$1.42

Volume

857,436

Day Range

$1.40 - $1.48

Enterprise Value

161.9M

Cash

300.7M

Avg Qtr Burn

-67.32M

Insider Ownership

18.08%

Institutional Own.

77.52%

Qtr Updated

12/31/25


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Drug & IndicationStage & EventCatalyst Date
AUCATZYL® (obecabtagene autoleucel) (obe-cel) Details
Acute lymphoblastic leukemia, Cancer, Blood cancer

Approved

Quarterly sales

Phase 2

Data readout

AUCATZYL/Obecabtagene Autoleucel (AUTO1) (CD19 CAR-T) Details
Pediatric Relapsed Or Refractory B-Cell Acute Lymphoblastic Leukemia And B-Cell Non-Hodgkin Lymphoma

Phase 2

Data readout

AUTO4 Details
Peripheral T cell cancer

Phase 1/2

Update

obe-cel (AUTO1) (CD19) Details
Lymphoma, Leukemia, Cancer, Central nervous system illness, primary central nervous system lymphomas

Phase 1

Data readout

AUTO1/22 (CD19 & CD22) Details
Cancer, Leukemia, Pediatric Acute lymphoblastic leukemia

Phase 1

Data readout

AUTO6NG Details
Solid tumor/s, Neuroblastoma

Phase 1

Data readout

AUTO8 (BCMA & CD19) (BCMA CD19 CAR-T) Details
Relapsed Or Refractory Light-Chain (AL) Amyloidosis

Phase 1

Data readout

AUTO8 (BCMA & CD19) (BCMA CD19 CAR-T) Details
Relapsed Or Refractory Light-Chain (AL) Amyloidosis

Phase 1

Data readout

Phase 1

Data readout

obe-cel (AUTO1) (CD19) Details
Systemic lupus erythematosus

Phase 1

Data readout

obe-cel (AUTO1) (CD19) Details
Lymphoma, Non-Hodgkin lymphoma, Chronic lymphocytic leukemia, Cancer, Leukemia

Phase 1

Update

Phase 1

Update

AUTO5 Details
T-cell lymphoma

Phase 1

Initiation

AUTO3 (CD19, CD22) Details
Lymphoma, Diffuse large B cell lymphoma, Cancer

Failed

Discontinued