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Cara Therapeutics NASDAQ:CARA Cara Therapeutics is a clinical-stage biopharmaceutical company focused on developing and commercializing new chemical entities designed to alleviate pruritus by selectively targeting peripheral kappa opioid receptors, or KORs. Cara is developing a novel and proprietary class of product candidates, led by KORSUVA™ (CR845/difelikefalin), a first-in-class KOR agonist that targets the body's peripheral nervous system, as well as certain immune cells. In two Phase 3 trials, KORSUVA injection has demonstrated statistically significant reductions in itch intensity and concomitant improvement in quality of life measures in hemodialysis patients with moderate-to-severe chronic kidney disease-associated pruritus (CKD-aP). Oral KORSUVA™ has successfully completed a Phase 2 trial for the treatment of pruritus in patients with CKD and is currently in Phase 2 trials in atopic dermatitis, primary biliary cholangitis and notalgia paresthetica patients with moderate-to-severe pruritus.
Location: 4 Stamford Plz, Connecticut, 06902-3834, US | Website: www.caratherapeutics.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing
Market Cap
NaN
52 Wk Range
$ - $
Previous Close
$N/A
Open
$N/A
Day Range
N/A - N/A
Volume
N/A
Avg Volume
N/A
Enterprise Value
4.943M
Cash
56.62M
Avg Qtr Burn
-19.98M
Short % of Float
2.38%
Insider Ownership
15.75%
Institutional Own.
32.74%
Qtr Updated
06/30/24
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Korsuva IV (CR845 IV) Details Pruritus with chronic kidney disease , Kidney disease | Approved Quarterly sales | |
Oral Korsuva (difelikefalin) (CR845) Details Pruritus with chronic kidney disease , Chronic kidney disease | Phase 3 Update | |
Oral Korsuva (difelikefalin) (CR845) Details Chronic liver disease, Liver disease, Chronic pruritus, Hemophilia, Blood disorder | Failed Discontinued | |
Oral Korsuva (difelikefalin) (CR845) Details Chronic pruritus, Pruritus associated with notalgia paresthetica | Failed Discontinued | |
Oral Korsuva (difelikefalin)(CR845) Details Inflammatory disease, Skin disease/disorder, Atopic dermatitis, Atopic pruritus | Failed Discontinued |