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Cara Therapeutics NASDAQ:CARA Cara Therapeutics is a clinical-stage biopharmaceutical company focused on developing and commercializing new chemical entities designed to alleviate pruritus by selectively targeting peripheral kappa opioid receptors, or KORs. Cara is developing a novel and proprietary class of product candidates, led by KORSUVA™ (CR845/difelikefalin), a first-in-class KOR agonist that targets the body's peripheral nervous system, as well as certain immune cells. In two Phase 3 trials, KORSUVA injection has demonstrated statistically significant reductions in itch intensity and concomitant improvement in quality of life measures in hemodialysis patients with moderate-to-severe chronic kidney disease-associated pruritus (CKD-aP). Oral KORSUVA™ has successfully completed a Phase 2 trial for the treatment of pruritus in patients with CKD and is currently in Phase 2 trials in atopic dermatitis, primary biliary cholangitis and notalgia paresthetica patients with moderate-to-severe pruritus.

Location: 4 Stamford Plz, Connecticut, 06902-3834, US | Website: www.caratherapeutics.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing

Market Cap

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52 Wk Range

$ - $

Previous Close

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Open

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Day Range

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Volume

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Avg Volume

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Enterprise Value

30.88M

Cash

37.9M

Avg Qtr Burn

-15.23M

Short % of Float

1.70%

Insider Ownership

13.07%

Institutional Own.

24.17%

Qtr Updated

12/31/24

Drug Pipeline

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Drug & Indication	Stage & Event	Catalyst Date
Korsuva IV (CR845 IV) Details Pruritus with chronic kidney disease , Kidney disease	Approved Quarterly sales	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Oral Korsuva (difelikefalin) (CR845) Details Chronic liver disease, Liver disease, Chronic pruritus, Hemophilia, Blood disorder	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Oral Korsuva (difelikefalin) (CR845) Details Pruritus with chronic kidney disease , Chronic kidney disease	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Oral Korsuva (difelikefalin) (CR845) Details Chronic pruritus, Pruritus associated with notalgia paresthetica	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Oral Korsuva (difelikefalin)(CR845) Details Inflammatory disease, Skin disease/disorder, Atopic dermatitis, Atopic pruritus	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.