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Centessa Pharmaceuticals NasdaqGS:CNTA Centessa Pharmaceuticals plc, a clinical-stage pharmaceutical company, discovers, develops, and delivers medicines. Its lead clinical-stage program includes ORX750, an orally administered OX2R agonist in a Phase 2a study for the treatment of idiopathic hypersomnia and narcolepsy type 1 and 2. The company also develops ORX142 for the treatment of neurological and neurodegenerative disorders, as well as other potential symptoms, including excessive daytime sleepiness, impaired attention, cognitive deficits, and fatigue; and ORX489 for the treatment of neuropsychiatric disorders. In addition, it offers LockBody, which is designed to selectively drive potent effector function activity, such as CD3, into the tumor microenvironment. Centessa Pharmaceuticals plc was incorporated in 2020 and is headquartered in Altrincham, the United Kingdom.

Location: 1 Ashley Road, Altrincham, WA14 2DT, United Kingdom | Website: https://centessa.com | Industry: Biotechnology | Sector: Healthcare

Market Cap

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52 Wk Range

$ - $

Previous Close

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Open

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Day Range

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Volume

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Avg Volume

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Enterprise Value

1.442B

Cash

284.5M

Avg Qtr Burn

-40.5M

Short % of Float

6.11%

Insider Ownership

0.34%

Institutional Own.

96.61%

Qtr Updated

03/31/25

Drug Pipeline

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Drug & Indication	Stage & Event	Catalyst Date
ORX750 Details Narcolepsy, Sleep-wake disorder	Phase 2a Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
ORX142 Details Acutely sleep-deprived healthy volunteers	Phase 1 Initiation	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Imgatuzumab Details Solid tumor/s, Cancer, Cutaneous squamous cell carcinoma	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
LB101 Details Cutaneous squamous cell carcinoma, Cancer, Solid tumor/s	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
SerpinPC Details Hemophilia	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Lixivaptan Details Kidney disease	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.