CRNX - Crinetics

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Crinetics NASDAQ:CRNX Crinetics Pharmaceuticals is a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. The company's lead product candidate, paltusotine (formerly CRN00808), is an oral selective nonpeptide somatostatin receptor type 2 biased agonist undergoing two Phase 2 clinical trials for the treatment of acromegaly, an orphan disease affecting more than 25,000 people in the United States. Crinetics plans to advance paltusotine into a Phase 3 trial in acromegaly and a Phase 2 trial for the treatment of carcinoid syndrome associated with NETs in 2021. The company is also developing CRN04777, an oral nonpeptide somatostatin receptor type 5 (SST5) agonist for hyperinsulinism, as well as an oral nonpeptide ACTH antagonist for the treatment of Cushing's disease, congenital adrenal hyperplasia and other diseases of excess ACTH. All of the company's drug candidates are new chemical entities resulting from in-house drug discovery efforts and are wholly owned by the company

Location: 10222 Barnes Canyon Rd Bldg 2, California, 92121-2711, United States | Website: www.crinetics.com | Industry: Research and Development in Biotechnology | Sector: Professional, Scientific, and Technical Services


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Enterprise Value

3.961B

Cash

863M

Avg Qtr Burn

-44.58M

Short % of Float

8.59%

Insider Ownership

1.87%

Institutional Own.

95.92%

Qtr Updated

06/30/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date

NDA

Acceptance for review

Paltusotine (SST2 agonist) Details
Neuroendocrine tumor, Carcinoid syndrome

Phase 3

Initiation

Phase 2

Data readout

Phase 2

Data readout

Failed

Discontinued