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Cyclacel Pharmaceuticals NASDAQ:CYCC Cyclacel Pharmaceuticals is a clinical-stage biopharmaceutical company using its expertise in cell cycle, transcriptional regulation and DNA damage response biology in cancer cells to develop innovative medicines. The transcriptional regulation program is evaluating CYC065, a CDK inhibitor, in patients with advanced solid cancers and in combination with venetoclax in patients with advanced hematological malignancies, including CLL and AML. The DNA damage response program is evaluating a sequential regimen of sapacitabine and seliciclib, a CDK inhibitor, in BRCA positive patients with advanced solid cancers and a concomitant regimen of sapacitabine and olaparib, a PARP inhibitor, in BRCA positive patients with breast cancer. CYC140, a PLK inhibitor, is in a Phase 1 first-in-human study in patients with advanced leukemias. Cyclacel's strategy is to build a diversified biopharmaceutical business focused in hematology and oncology based on a pipeline of novel drug candidates.
Location: 200 Connell Dr Ste 1500, New Jersey, 07922-2811, US | Website: www.cyclacel.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing
Market Cap
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52 Wk Range
$ - $
Previous Close
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Open
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Day Range
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Volume
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Avg Volume
N/A
Enterprise Value
-3.902M
Cash
6.00M
Avg Qtr Burn
-2.878M
Short % of Float
3.09%
Insider Ownership
5.46%
Institutional Own.
18.03%
Qtr Updated
06/30/24
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Oral Fadraciclib (CDK2 & CDK9) Details Lymphoma, Solid tumor/s, Cancer | Phase 2 Data readout | |
Oral Plogosertib Details Lymphoma, Solid tumor/s | Phase 1 Data readout |