CYCN - Cyclerion Therapeutics

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Cyclerion Therapeutics NASDAQ:CYCN Cyclerion Therapeutics is a clinical-stage biopharmaceutical company on a mission to develop treatments that restore cognitive function. Cyclerion's lead program is CY6463, a novel, first-in-class, CNS-penetrant, sGC stimulator that modulates a key node in a fundamental CNS signaling network. The multidimensional pharmacology elicited by the stimulation of sGC has the potential to impact a broad range of CNS diseases. CY6463 has shown rapid improvement in biomarkers associated with cognitive impairment and is currently in clinical development for Alzheimer's Disease with Vascular pathology (ADv) and Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like episodes (MELAS).

Location: | Website: www.cyclerion.com | Industry: Research and Development in Biotechnology | Sector: Professional, Scientific, and Technical Services


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52 Wk Range

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Volume

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Enterprise Value

2.331M

Cash

4.588M

Avg Qtr Burn

-2.863M

Short % of Float

1.10%

Insider Ownership

21.90%

Institutional Own.

40.63%

Qtr Updated

06/30/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
Zagociguat (CY6463) Details
Neurological disorder, Alzheimer's disease, Dementia

Phase 2

Update

Zagociguat (CY6463) Details
Cognitive Impairment Associated with Schizophrenia

Phase 1b

Update

Failed

Discontinued

Olinciguat Details
Sickle cell disease

Failed

Discontinued

Zagociguat (CY6463) Details
Rare diseases, Mitochondrial disease, Rare genetic disease

Failed

Discontinued