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Cyclerion Therapeutics NasdaqCM:CYCN Cyclerion Therapeutics, Inc., a biopharmaceutical company, develops treatments for serious diseases serious diseases with novel sGC stimulators in both the central nervous system (CNS) and the periphery. It is developing Olinciguat, an orally administered vascular soluble guanylate cyclase (sGC) stimulator, which is in Phase 2 clinical trial to treat cardiovascular diseases; and Praliciguat, a systemic sGC stimulator for the treatment of rare kidney disease. It has a license agreement with Akebia to develop, manufacture, medical affair, and commercializes Praliciguat and other related products. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

Location: 245 First Street, Riverview II, Cambridge, MA, 02142, United States | Website: https://www.cyclerion.com | Industry: Biotechnology | Sector: Healthcare

Market Cap

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52 Wk Range

$ - $

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Day Range

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Volume

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Avg Volume

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Enterprise Value

5.253M

Cash

3.639M

Avg Qtr Burn

-857.5K

Short % of Float

1.09%

Insider Ownership

32.73%

Institutional Own.

12.22%

Qtr Updated

03/31/25

Drug Pipeline

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Drug & Indication	Stage & Event	Catalyst Date
Zagociguat (CY6463) Details Neurological disorder, Alzheimer's disease, Dementia	Phase 2 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Zagociguat (CY6463) Details Cognitive Impairment Associated with Schizophrenia	Phase 1b Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Zagociguat (CY6463) Details Rare diseases, Mitochondrial disease, Rare genetic disease	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Praliciguat (sGC stimulator) Details Heart disease	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Olinciguat Details Sickle cell disease	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.