Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. It also develops Aficamten, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of HCM; and omecamtiv mecarbil, a potential treatment across the continuum of care in heart failure with severely reduced ejection fraction. In addition, the company is involved in developing and Ulacamten, a novel, selective, oral, and small molecule cardiac myosin inhibitor designed to reduce the hypercontractility associated with heart failure with preserved ejection fraction in Phase 1 clinical trials; and CK-089, a fast skeletal muscle troponin activator in Phase 1 clinical trials. Cytokinetics, Incorporated was incorporated in 1997 and is headquartered in South San Francisco, California. Show more

350 Oyster Point Boulevard, South San Francisco, CA, 94080, United States

Biotechnology
Healthcare

Market Cap

7.397B

52 Wk Range

$29.31 - $70.98

Previous Close

$60.06

Open

$61.03

Volume

2,098,864

Day Range

$59.18 - $61.92

Enterprise Value

7.799B

Cash

882.2M

Avg Qtr Burn

-142.7M

Insider Ownership

1.05%

Institutional Own.

-

Qtr Updated

12/31/25


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Drug & IndicationStage & EventCatalyst Date
Aficamten Details
Obstructive hypertrophic cardiomyopathy (oHCM)

Approved

Update

Aficamten Details
Hypertrophic cardiomyopathies

PDUFA

Approval decision

Aficamten Details
non-obstructive hypertropic cardiomyopathy (nHCM)

Phase 3

Data readout

Omecamtiv Mecarbil (cardiac myosin activator) Details
Pancreatic cancer, Heart disease, Heart failure

Phase 3

Update

Aficamten Details
Hypertrophic cardiomyopathies

Phase 3

Update

Phase 2

Update

Phase 1

Data readout

CK-3828136 (CK-136) (cardiac troponin activator) Details
Heart failure, Heart disease, Epilepsy

Phase 1

Update

Failed

Discontinued