Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. It also develops Aficamten, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of HCM; and omecamtiv mecarbil, a potential treatment across the continuum of care in heart failure with severely reduced ejection fraction. In addition, the company is involved in developing and Ulacamten, a novel, selective, oral, and small molecule cardiac myosin inhibitor designed to reduce the hypercontractility associated with heart failure with preserved ejection fraction in Phase 1 clinical trials; and CK-089, a fast skeletal muscle troponin activator in Phase 1 clinical trials. Cytokinetics, Incorporated was incorporated in 1997 and is headquartered in South San Francisco, California. Show more
350 Oyster Point Boulevard, South San Francisco, CA, 94080, United States
Market Cap
7.397B
52 Wk Range
$29.31 - $70.98
Previous Close
$60.06
Open
$61.03
Volume
2,098,864
Day Range
$59.18 - $61.92
Enterprise Value
7.799B
Cash
882.2M
Avg Qtr Burn
-142.7M
Insider Ownership
1.05%
Institutional Own.
-
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Aficamten Details Obstructive hypertrophic cardiomyopathy (oHCM) | Approved Update | |
Aficamten Details Hypertrophic cardiomyopathies | PDUFA Approval decision | |
Aficamten Details non-obstructive hypertropic cardiomyopathy (nHCM) | Phase 3 Data readout | |
Omecamtiv Mecarbil (cardiac myosin activator) Details Pancreatic cancer, Heart disease, Heart failure | Phase 3 Update | |
Aficamten Details Hypertrophic cardiomyopathies | Phase 3 Update | |
CK-4021586 (CK-586) (cardiac myosin inhibitor) Details Heart disease, Heart failure | Phase 2 Update | |
CK-4015089 (CK-089) Details Muscular dystrophy | Phase 1 Data readout | |
CK-3828136 (CK-136) (cardiac troponin activator) Details Heart failure, Heart disease, Epilepsy | Phase 1 Update | |
Reldesemtiv (CK-601) (next-generation fast skeletal muscle troponin activator (FSTA)) Details Amyotrophic lateral sclerosis, Neurodegenerative disease | Failed Discontinued |
