Eledon Pharmaceuticals, Inc. operates as a clinical stage biotechnology company. It uses its immunology expertise in targeting the CD40 Ligand (CD40L) pathway to develop therapies to protect transplanted organs and prevent rejection, and to treat amyotrophic lateral sclerosis (ALS). The company's lead compound in development is tegoprubart, an IgG1 and anti-CD40L antibody with high affinity for CD40 Ligand, a biological target with therapeutic potential. It is also developing its products for the prevention of allograft rejection in kidney transplantation and xenotransplantation. The company has a collaboration agreement with eGenesis, Inc.; and a strategic collaboration with NewcelX Ltd. for the development of the NCEL-101 therapy for Type 1 Diabetes. The company was formerly known as Novus Therapeutics, Inc. and changed its name to Eledon Pharmaceuticals, Inc. in January 2021. Eledon Pharmaceuticals, Inc. is headquartered in Irvine, California. Show more
19800 MacArthur Boulevard, Irvine, CA, 92612, United States
Market Cap
238.9M
52 Wk Range
$1.35 - $4.60
Previous Close
$3.00
Open
$2.94
Volume
397,055
Day Range
$2.90 - $3.14
Enterprise Value
94.86M
Cash
133.3M
Avg Qtr Burn
-14.09M
Insider Ownership
1.14%
Institutional Own.
61.24%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Tegoprubart (AT-1501) Details Kidney transplantation | Phase 3 Initiation | |
Tegoprubart (AT-1501) Details Type 1 diabetes, Islet Cell Transplantation | Phase 2 Update | |
Tegoprubart (AT-1501) Details Amyotrophic lateral sclerosis | Phase 2 Update | |
Tegoprubart (AT-1501) (Anti-CD40L Antibody) Details Kidney Transplant Tolerance Induction | Phase 2 Initiation | |
Tegoprubart (AT-1501) (Anti-CD40L Antibody) Details Islet Cell Transplantation In Renal Dysfunction | Phase 2 Initiation | |
Tegoprubart (AT-1501) (Anti-CD40L Antibody) Details Liver Transplantation | Phase 2 Initiation | |
Tegoprubart (AT-1501) Details Kidney transplantation | Phase 1b Update | |
Tegoprubart (AT-1501) Details Autoimmune nephritis | Failed Discontinued | |
Tegoprubart (AT-1501) Details IgA nephropathy | Failed Discontinued |
