Eledon Pharmaceuticals, Inc. operates as a clinical stage biotechnology company. It uses its immunology expertise in targeting the CD40 Ligand (CD40L) pathway to develop therapies to protect transplanted organs and prevent rejection, and to treat amyotrophic lateral sclerosis (ALS). The company's lead compound in development is tegoprubart, an IgG1 and anti-CD40L antibody with high affinity for CD40 Ligand, a biological target with therapeutic potential. It is also developing its products for the prevention of allograft rejection in kidney transplantation and xenotransplantation. The company has a collaboration agreement with eGenesis, Inc.; and a strategic collaboration with NewcelX Ltd. for the development of the NCEL-101 therapy for Type 1 Diabetes. The company was formerly known as Novus Therapeutics, Inc. and changed its name to Eledon Pharmaceuticals, Inc. in January 2021. Eledon Pharmaceuticals, Inc. is headquartered in Irvine, California. Show more

19800 MacArthur Boulevard, Irvine, CA, 92612, United States

Biotechnology
Healthcare

Market Cap

238.9M

52 Wk Range

$1.35 - $4.60

Previous Close

$3.00

Open

$2.94

Volume

397,055

Day Range

$2.90 - $3.14

Enterprise Value

94.86M

Cash

133.3M

Avg Qtr Burn

-14.09M

Insider Ownership

1.14%

Institutional Own.

61.24%

Qtr Updated

12/31/25


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Drug & IndicationStage & EventCatalyst Date
Tegoprubart (AT-1501) Details
Kidney transplantation

Phase 3

Initiation

Tegoprubart (AT-1501) Details
Type 1 diabetes, Islet Cell Transplantation

Phase 2

Update

Tegoprubart (AT-1501) Details
Amyotrophic lateral sclerosis

Phase 2

Update

Tegoprubart (AT-1501) (Anti-CD40L Antibody) Details
Kidney Transplant Tolerance Induction

Phase 2

Initiation

Tegoprubart (AT-1501) (Anti-CD40L Antibody) Details
Islet Cell Transplantation In Renal Dysfunction

Phase 2

Initiation

Phase 2

Initiation

Tegoprubart (AT-1501) Details
Kidney transplantation

Phase 1b

Update

Tegoprubart (AT-1501) Details
Autoimmune nephritis

Failed

Discontinued

Failed

Discontinued