Galera Therapeutics, Inc., a biopharmaceutical company, focuses on the development of a portfolio of small molecule dismutase (SOD) mimetics to improve radiotherapy in cancer. The company's lead product is tilarginine that is in Phase 1/2 trial of a pan-inhibitor of nitric oxide synthase to treat patients with highly resistant forms of breast cancer, including metaplastic breast cancer (MpBC) and other refractory subsets of triple-negative breast cancer (TNBC). It develops avasopasem manganese, a small molecule dismutase mimetic for the treatment of radiotherapy induced severe oral mucositis in patients with head and neck cancer (HNC); for the treatment of radiotherapy-induced esophagitis in patients with lung cancer; and for patients with HNC undergoing standard-of-care radiotherapy that is in Phase 2a clinical trial. The company was incorporated in 2012 and is based in Malvern, Pennsylvania. Show more

Location: 101 Lindenwood Drive, Malvern, PA, 19355, United States | Website: https://www.galeratx.com | Industry: Biotechnology | Sector: Healthcare


Market Cap

2.113M

52 Wk Range

$0.01 - $0.06

Previous Close

$0.03

Open

$0.03

Volume

116,424

Day Range

$0.03 - $0.03

Enterprise Value

-2.482M

Cash

5.23M

Avg Qtr Burn

-2.083M

Insider Ownership

32.70%

Institutional Own.

9.99%

Qtr Updated

06/30/25


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
Tilarginine + paclitaxel Details
Cancer, Triple Negative Breast Cancer (TNBC)

Phase 2

Initiation

Phase 1/2

Data readout

Avasopasem + (fulvestrant +CDK4/6i) Details
Cancer, HR+/HER2-Metastatic Breast Cancer

Phase 1/2

Initiation

Rucosopasem Details
Cancer, Non-small cell lung carcinoma

Failed

Discontinued

Rucosopasem Details
Pancreatic cancer, Cancer

Failed

Discontinued

Avasopasem Manganese (GC4419) Details
Head and neck cancer, Cancer

Failed

Discontinued

Avasopasem Manganese (GC4419) Details
Lung cancer, Esophagitis, Non-small cell lung carcinoma

Failed

Discontinued

Avasopasem Manganese (GC4419) Details
Infectious disease, COVID-19

Failed

Discontinued