HGEN - Humanigen Inc.

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Humanigen Inc. NASDAQ:HGEN Humanigen, Inc. is developing its portfolio of Humaneered® monoclonal antibodies to address cutting-edge CAR-T optimization and oncology treatments advancing safer, better, and more effective cancer therapies. Derived from the company's Humaneered® platform, lenzilumab and ifabotuzumab are monoclonal antibodies with first-in-class mechanisms. Lenzilumab, which targets GM-CSF, is in development as a potential biologic therapy to make CAR-T therapy safer and more effective, as well as a potential treatment for rare hematologic cancers such as CMML and JMML. Ifabotuzumab, which targets the Eph type-A receptor 3 (EphA3), is being explored as a potential treatment for glioblastoma multiforme (GBM) and other deadly cancers, both as naked antibody and as part of an antibody-drug conjugate, as well as a backbone for a novel CAR-T construct, and a bispecific antibody platform.

Location: 533 Airport Blvd Ste 400, California, 94010-2013, US | Website: www.humanigen.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing


Market Cap

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52 Wk Range

$ - $

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Enterprise Value

0.00

Cash

0.00

Avg Qtr Burn

N/A

Short % of Float

3.75%

Insider Ownership

10.35%

Institutional Own.

0.49%

Qtr Updated

03/31/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
Lenzilumab Details
Graft-versus-host disease

Phase 2/3

Data readout

Lenzilumab Details
Leukemia, Chronic myelomonocytic leukemia

Phase 2/3

Interim update

Ifabotuzumab (iFab) Details
Glioblastoma, Cancer

Phase 1b

Initiation

Failed

Discontinued

Lenzilumab Details
Cancer, Non-Hodgkin lymphoma

Failed

Discontinued

Lenzilumab with CAR-T Details
B-cell malignancies, Cancer

Failed

Discontinued

Lenzilumab Details
Respiratory conditions, Asthma

Failed

Discontinued