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Humanigen Inc. NASDAQ:HGEN Humanigen, Inc. is developing its portfolio of Humaneered® monoclonal antibodies to address cutting-edge CAR-T optimization and oncology treatments advancing safer, better, and more effective cancer therapies. Derived from the company's Humaneered® platform, lenzilumab and ifabotuzumab are monoclonal antibodies with first-in-class mechanisms. Lenzilumab, which targets GM-CSF, is in development as a potential biologic therapy to make CAR-T therapy safer and more effective, as well as a potential treatment for rare hematologic cancers such as CMML and JMML. Ifabotuzumab, which targets the Eph type-A receptor 3 (EphA3), is being explored as a potential treatment for glioblastoma multiforme (GBM) and other deadly cancers, both as naked antibody and as part of an antibody-drug conjugate, as well as a backbone for a novel CAR-T construct, and a bispecific antibody platform.
Location: 533 Airport Blvd Ste 400, California, 94010-2013, US | Website: www.humanigen.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing
Market Cap
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52 Wk Range
$ - $
Previous Close
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Open
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Day Range
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Avg Volume
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Enterprise Value
0.00
Cash
0.00
Avg Qtr Burn
N/A
Short % of Float
3.75%
Insider Ownership
10.35%
Institutional Own.
0.49%
Qtr Updated
03/31/24
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
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Lenzilumab Details Graft-versus-host disease | Phase 2/3 Data readout | |
Lenzilumab Details Leukemia, Chronic myelomonocytic leukemia | Phase 2/3 Interim update | |
Ifabotuzumab (iFab) Details Glioblastoma, Cancer | Phase 1b Initiation | |
Lenzilumab Details COVID-19 | Failed Discontinued | |
Lenzilumab Details Cancer, Non-Hodgkin lymphoma | Failed Discontinued | |
Lenzilumab with CAR-T Details B-cell malignancies, Cancer | Failed Discontinued | |
Lenzilumab Details Respiratory conditions, Asthma | Failed Discontinued |