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Kalvista Pharmaceuticals NASDAQ:KALV KalVista Pharmaceuticals, Inc. is a pharmaceutical company focused on the discovery, development, and commercialization of small molecule protease inhibitors for diseases with significant unmet need. KalVista has developed a proprietary portfolio of novel, small molecule plasma kallikrein inhibitors initially targeting hereditary angioedema (HAE) and diabetic macular edema (DME). KalVista is developing KVD900 as an oral on-demand therapy for acute HAE attacks, which completed a Phase 2 efficacy trial in February 2021, demonstrating statistical and clinical significance across all endpoints. KVD824 is in development for prophylactic treatment of HAE with a Phase 2 clinical trial expected to initiate in the second quarter of 2021. In addition, KalVista's oral Factor XIIa inhibitor program represents a new generation of therapies that may further improve the treatment of HAE for patients. In DME, an intravitreally administered plasma kallikrein inhibitor, called KVD001, has completed a Phase 2 clinical trial.
Location: 55 Cambridge Pkwy Ste 901E, Massachusetts, 02142-1234, US | Website: www.kalvista.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing
Market Cap
NaN
52 Wk Range
$ - $
Previous Close
$N/A
Open
$N/A
Day Range
N/A - N/A
Volume
N/A
Avg Volume
N/A
Enterprise Value
317.7M
Cash
174.3M
Avg Qtr Burn
-25.68M
Short % of Float
24.95%
Insider Ownership
1.44%
Institutional Own.
-
Qtr Updated
07/31/24
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Sebetralstat (KVD900) (film coated) Details Hereditary angioedema , Rare diseases, Rare genetic disease | PDUFA Approval decision | |
Sebetralstat (KVD900) (film coated) Details Hereditary angioedema , Rare genetic disease, Rare diseases | Phase 3 Update | |
KVD001 (IVT) Details Diabetic macular edema, Frontotemporal dementia with C9orf72 mutation, Dementia, Diabetes | Failed Discontinued | |
KVD824 (plasma kallikrein enzyme inhibitor) Details Hereditary angioedema , Rare diseases, Rare genetic disease | Failed Discontinued |