KURA - Kura Oncology

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Kura Oncology NASDAQ:KURA Tipifarnib, is a potent, selective and orally bioavailable inhibitor of farnesyl transferase in-licensed from Janssen. Previously, tipifarnib was studied in more than 5,000 cancer patients and showed compelling and durable anti-cancer activity in certain patient subsets; however, no molecular mechanism of action had been determined that could explain its clinical activity across a range of solid tumor and hematologic indications. Leveraging advances in next generation sequencing as well as emerging information about cancer genetics and tumor biology, the Company is seeking to identify those patients most likely to benefit from tipifarnib. In addition to Breakthrough Therapy Designation, tipifarnib has been granted Fast Track designation by the FDA for the treatment of patients with HRAS mutant HNSCC. In addition to HNSCC, tipifarnib has demonstrated encouraging clinical activity in a number of additional genetically defined tumor types. Kura has received multiple issued patents for tipifarnib, providing patent exclusivity in the U.S. and foreign countries. About Kura Oncology

Location: 12730 High Bluff Drive, Suite 400, California, 92130, US | Website: www.kuraoncology.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing


Market Cap

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52 Wk Range

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Previous Close

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Day Range

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Volume

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Avg Volume

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Enterprise Value

881.6M

Cash

491.5M

Avg Qtr Burn

-38.68M

Short % of Float

20.76%

Insider Ownership

1.07%

Institutional Own.

-

Qtr Updated

06/30/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
Tipifarnib Details
Cancer, Head and neck cancer, Head and neck squamous cell carcinoma

Phase 2

Data readout

Ziftomenib Details
Acute myeloid leukemia, Blood cancer, Cancer

Phase 2

Data readout

Tipifarnib Details
Cancer, Lymphoma, T-cell lymphoma

Phase 2

Update

Tipifarnib + alpelisib Details
Head and neck cancer, Head and neck squamous cell carcinoma, Cancer

Phase 1/2

Update

KO-2806 (FTI inhibitor) Details
Solid tumor/s, Non-small cell lung carcinoma, Cancer

Phase 1

Data readout

KO-2806 (FTI inhibitor) + cabozantinib Details
Solid tumor/s, Renal cell carcinoma, Cancer

Phase 1

Data readout

Ziftomenib + gilteritinib Details
Acute myeloid leukemia, Blood cancer, Cancer

Phase 1

Data readout

Phase 1

Data readout

Ziftomenib Details
Cancer, Gastrointestinal stromal tumors

Phase 1

Initiation