
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Kura Oncology NASDAQ:KURA Tipifarnib, is a potent, selective and orally bioavailable inhibitor of farnesyl transferase in-licensed from Janssen. Previously, tipifarnib was studied in more than 5,000 cancer patients and showed compelling and durable anti-cancer activity in certain patient subsets; however, no molecular mechanism of action had been determined that could explain its clinical activity across a range of solid tumor and hematologic indications. Leveraging advances in next generation sequencing as well as emerging information about cancer genetics and tumor biology, the Company is seeking to identify those patients most likely to benefit from tipifarnib. In addition to Breakthrough Therapy Designation, tipifarnib has been granted Fast Track designation by the FDA for the treatment of patients with HRAS mutant HNSCC. In addition to HNSCC, tipifarnib has demonstrated encouraging clinical activity in a number of additional genetically defined tumor types. Kura has received multiple issued patents for tipifarnib, providing patent exclusivity in the U.S. and foreign countries. About Kura Oncology
Location: 12730 High Bluff Drive, Suite 400, California, 92130, US | Website: www.kuraoncology.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing
Market Cap
NaN
52 Wk Range
$ - $
Previous Close
$N/A
Open
$N/A
Day Range
N/A - N/A
Volume
N/A
Avg Volume
N/A
Enterprise Value
202.9M
Cash
455.3M
Avg Qtr Burn
-42.28M
Short % of Float
14.22%
Insider Ownership
1.19%
Institutional Own.
-
Qtr Updated
09/30/24
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
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Ziftomenib Details Acute myeloid leukemia, Blood cancer, Cancer | NDA Submission | |
Ziftomenib + venetoclax + azacitidine Details Blood cancer, Acute myeloid leukemia, Cancer | Phase 3 Initiation | |
Ziftomenib + Induction Chemotherapy (7+3) Details Blood cancer, Acute myeloid leukemia, Cancer | Phase 3 Initiation | |
Tipifarnib Details Cancer, Head and neck cancer, Head and neck squamous cell carcinoma | Phase 2 Data readout | |
Tipifarnib Details Cancer, Lymphoma, T-cell lymphoma | Phase 2 Update | |
Tipifarnib + alpelisib Details Head and neck cancer, Head and neck squamous cell carcinoma, Cancer | Phase 1/2 Data readout | |
Ziftomenib + venetoclax/azacitidine Details Blood cancer, Acute myeloid leukemia, Cancer | Phase 1b Data readout | |
Ziftomenib + venetoclax/azacitidine (ven/aza) or cytarabine/daunorubicin (7+3) Details Blood cancer, Acute myeloid leukemia, Cancer | Phase 1b Data readout | |
Ziftomenib + gilteritinib Details Acute myeloid leukemia, Blood cancer, Cancer | Phase 1 Data readout | |
KO-2806 (FTI inhibitor) + cabozantinib Details Solid tumor/s, Renal cell carcinoma, Cancer | Phase 1 Data readout | |
KO-2806 (FTI inhibitor) Details Solid tumor/s, Non-small cell lung carcinoma, Cancer | Phase 1 Data readout | |
Ziftomenib Details Cancer, Gastrointestinal stromal tumors | Phase 1 Initiation |