LPTX - Leap Therapeutics

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Leap Therapeutics NASDAQ:LPTX Leap Therapeutics is focused on developing targeted and immuno-oncology therapeutics. Leap's most advanced clinical candidate, DKN-01, is a humanized monoclonal antibody targeting the Dickkopf-1 (DKK1) protein, a Wnt pathway modulator. DKN-01 is in clinical trials in patients with esophagogastric, hepatobiliary, gynecologic, and prostate cancers. Leap has entered into a strategic partnership with BeiGene, Ltd. for the rights to develop DKN-01 in Asia (excluding Japan), Australia, and New Zealand.

Location: 47 Thorndike St Ste B1-1, Massachusetts, 02141-1799, US | Website: www.leaptx.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing


Market Cap

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52 Wk Range

$ - $

Previous Close

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Day Range

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Volume

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Avg Volume

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Enterprise Value

38.33M

Cash

78.48M

Avg Qtr Burn

-12.51M

Short % of Float

3.38%

Insider Ownership

14.13%

Institutional Own.

40.28%

Qtr Updated

06/30/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
DKN-01 (+/- Paclitaxel) Details
Cancer, Carcinosarcoma, Ovarian cancer, Endometrial cancer

Phase 3

Update

Phase 2

Data readout

DKN-01 + pembrolizumab Details
Endometrial cancer, Cancer

Phase 2

Data readout

DKN-01 (+ tislelizumab +/- CAPOX) Details
Gastroesophageal junction tumors, Cancer, Gastric cancer

Phase 2a

Data readout

FL-301 Details
Cancer, Pancreatic cancer, Gastric cancer

Phase 1

Data readout

Failed

Discontinued