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Leap Therapeutics NasdaqCM:LPTX Leap Therapeutics, Inc., a biopharmaceutical company, acquires and develops antibody therapies for the treatment of cancer. Its lead clinical stage drug candidate includes DKN-01, a monoclonal antibody that inhibits Dickkopf-related protein 1, which is in various ongoing clinical trials for treating esophagogastric and gynecologic cancers, and colorectal cancer. The company also develops FL-501, a monoclonal antibody that inhibits GDF-15 protein that is in preclinical trial. It has an option and license agreement with Adimab, LLC and BeiGene, Ltd. to develop and commercialize DKN-01 in Asia (excluding Japan), Australia, and New Zealand. The company was formerly known as HealthCare Pharmaceuticals, Inc. and changed its name to Leap Therapeutics, Inc. in November 2015. Leap Therapeutics, Inc. was incorporated in 2011 and is based in Cambridge, Massachusetts.

Location: 47 Thorndike Street, Cambridge, MA, 02141, United States | Website: https://www.leaptx.com | Industry: Biotechnology | Sector: Healthcare

Market Cap

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52 Wk Range

$ - $

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Volume

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Avg Volume

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Enterprise Value

-31.51M

Cash

47.25M

Avg Qtr Burn

-15.07M

Short % of Float

6.89%

Insider Ownership

3.37%

Institutional Own.

49.32%

Qtr Updated

12/31/24

Drug Pipeline

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Drug & Indication	Stage & Event	Catalyst Date
Sirexatamab (DKN-01) + Pembrolizumab Details Cancer, Endometrial cancer	Phase 2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Sirexatamab (DKN-01) + Bevacizumab and Chemotherapy Details Advanced microsatellite stable colorectal cancer	Phase 2 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Sirexatamab (DKN-01) +/- Paclitaxel Details Cancer, Carcinosarcoma, Ovarian cancer, Endometrial cancer	Phase 2 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
FL-301 Details Cancer, Pancreatic cancer, Gastric cancer	Phase 1 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Sirexatamab (DKN-01) +/- Docetaxel Details Prostate cancer	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Sirexatamab (DKN-01) + Tislelizumab +/- CAPOX Details Gastroesophageal junction tumors, Cancer, Gastric cancer	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.