LPTX - Leap Therapeutics

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Leap Therapeutics NASDAQ:LPTX Leap Therapeutics is focused on developing targeted and immuno-oncology therapeutics. Leap's most advanced clinical candidate, DKN-01, is a humanized monoclonal antibody targeting the Dickkopf-1 (DKK1) protein, a Wnt pathway modulator. DKN-01 is in clinical trials in patients with esophagogastric, hepatobiliary, gynecologic, and prostate cancers. Leap has entered into a strategic partnership with BeiGene, Ltd. for the rights to develop DKN-01 in Asia (excluding Japan), Australia, and New Zealand.

Location: 47 Thorndike St Ste B1-1, Massachusetts, 02141-1799, US | Website: www.leaptx.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing


Market Cap

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52 Wk Range

$ - $

Previous Close

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Open

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Day Range

N/A - N/A

Volume

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Avg Volume

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Enterprise Value

-31.54M

Cash

47.25M

Avg Qtr Burn

-15.07M

Short % of Float

11.99%

Insider Ownership

3.24%

Institutional Own.

48.63%

Qtr Updated

12/31/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
Sirexatamab (DKN-01) + Pembrolizumab Details
Cancer, Endometrial cancer

Big Mover™

Susp. Mover™

Phase 2

Data readout

Sirexatamab (DKN-01) + Bevacizumab and Chemotherapy Details
Cancer, Advanced microsatellite stable colorectal cancer

Phase 2

Update

Sirexatamab (DKN-01) +/- Paclitaxel Details
Cancer, Carcinosarcoma, Ovarian cancer, Endometrial cancer

Phase 2

Update

FL-301 Details
Cancer, Pancreatic cancer, Gastric cancer

Phase 1

Data readout

Failed

Discontinued

Sirexatamab (DKN-01) + Tislelizumab +/- CAPOX Details
Gastroesophageal junction tumors, Cancer, Gastric cancer

Failed

Discontinued