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Madrigal Pharmaceuticals NASDAQ:MDGL Madrigal Pharmaceuticals is a clinical-stage biopharmaceutical company pursuing novel therapeutics that target a specific thyroid hormone pathway in the liver, which is a key regulatory mechanism common to a spectrum of cardio-metabolic and fatty liver diseases with high unmet medical need. Madrigal recognizes that compounds with greater selectivity for thyroid hormone receptor (THR)-ß and liver uptake has the greatest potential to overcome challenges faced by prior, less selective compounds and deliver the full therapeutic potential of THR-ß agonism. The Company believes that resmetirom, its lead product candidate, is the first orally administered, small-molecule, liver-directed, truly ß-selective THR agonist.

Location: 500 Office Center Dr Ste 400, Pennsylvania, 19034-3234, US | Website: www.madrigalpharma.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing

Market Cap

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52 Wk Range

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Previous Close

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Day Range

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Volume

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Avg Volume

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Enterprise Value

6.409B

Cash

926.3M

Avg Qtr Burn

-113.9M

Short % of Float

35.46%

Insider Ownership

8.79%

Institutional Own.

Qtr Updated

12/31/24

Drug Pipeline

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Drug & Indication	Stage & Event	Catalyst Date
Rezdiffra (Resmetirom) (MGL-3196) Details Non-alcoholic steatohepatitis , Liver disease	Approved Quarterly sales	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Resmetirom (MGL-3196) Details Fatty liver disease, Liver disease	Phase 3 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Rezdiffra (Resmetirom) (MGL-3196) Details Liver disease, Cirrhosis	Phase 3 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.