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Madrigal Pharmaceuticals NASDAQ:MDGL Madrigal Pharmaceuticals is a clinical-stage biopharmaceutical company pursuing novel therapeutics that target a specific thyroid hormone pathway in the liver, which is a key regulatory mechanism common to a spectrum of cardio-metabolic and fatty liver diseases with high unmet medical need. Madrigal recognizes that compounds with greater selectivity for thyroid hormone receptor (THR)-ß and liver uptake has the greatest potential to overcome challenges faced by prior, less selective compounds and deliver the full therapeutic potential of THR-ß agonism. The Company believes that resmetirom, its lead product candidate, is the first orally administered, small-molecule, liver-directed, truly ß-selective THR agonist.
Location: 500 Office Center Dr Ste 400, Pennsylvania, 19034-3234, US | Website: www.madrigalpharma.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing
Market Cap
NaN
52 Wk Range
$ - $
Previous Close
$N/A
Open
$N/A
Day Range
N/A - N/A
Volume
N/A
Avg Volume
N/A
Enterprise Value
5.848B
Cash
998.6M
Avg Qtr Burn
-107.8M
Short % of Float
39.89%
Insider Ownership
8.56%
Institutional Own.
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Qtr Updated
09/30/24
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Rezdiffra (Resmetirom) (MGL-3196) (THR-B Agonist) Details Non-alcoholic steatohepatitis , Liver disease | Approved Quarterly sales | |
Rezdiffra (Resmetirom) (MGL-3196) (THR-B Agonist) Details Liver disease, Cirrhosis | Phase 3 Data readout | |
Resmetirom (MGL-3196) (THR-B Agonist) Details Fatty liver disease, Liver disease | Phase 3 Data readout |