Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally. The company is also involved in the commercialization of Cholbam, a cholic acid capsule, which is approved as treatment for pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects and for adjunctive treatment of patients with peroxisomal disorders, including peroxisome biogenesis disorder-Zellweger spectrum disorder and Smith-Lemli-Opitz syndrome; and Chenodal, a tablet, which is approved for the treatment of radiolucent stones in the gallbladder, and under development for the treatment cerebrotendinous xanthomatosis. In addition, it develops Volixibat, an oral and minimally absorbed agent designed to inhibit IBAT, currently under Phase 2b clinical trial for the treatment of adult patients with cholestatic liver diseases; Brelovitug, for the treatment of chronic HDV infection, which is in Phase 2 clinical trial; and MRM-3379, that is in Phase 2 clinical study for the treatment of FXS. The company has a collaboration agreement with the Shire International GmbH; License Agreement with Pfizer Inc.; Sanofi-Aventis Deutschland GmbH; Novartis Pharma AG; Lonza Ltd.; Enthorin Therapeutics, LLC and Dart Neuroscience LLC; Asset Purchase Agreement with Asklepion Pharmaceuticals, LLC; License and Manufacturing Agreement with LGM Pharma; and Asset Purchase Agreement with Travere Therapeutics, Inc. The company was incorporated in 2018 and is headquartered in Foster City, California. Show more
950 Tower Lane, Foster City, CA, 94404, United States
Market Cap
5.471B
52 Wk Range
$36.88 - $109.28
Previous Close
$90.66
Open
$90.76
Volume
724,433
Day Range
$90.15 - $93.50
Enterprise Value
5.409B
Cash
383.3M
Avg Qtr Burn
N/A
Insider Ownership
1.48%
Institutional Own.
-
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
CTEXLI™ (chenodiol) Tablets Details Cerebrotendinous xanthomatosis | Approved Quarterly sales | |
LIVMARLI (Maralixibat) Details ALGS (Alagille syndrome), PFIC (Progressive Familial Intrahepatic Cholestasis) | Approved Quarterly sales | |
LIVMARLI/Maralixibat (IBAT Inhibitor) Details Pruritus In Rare Cholestatic Conditions | Phase 3 Data readout | |
Brelovitug (HBsAg Antibody) Details Chronic Hepatitis Delta Virus (HDV) | Phase 3 Data readout | |
Brelovitug (Monoclonal Antibody) Details Chronic Hepatitis Delta Virus (HDV) | Phase 3 Data readout | |
Volixibat Details Primary biliary cholangitis, Liver disease | Phase 2b Data readout | |
Volixibat Details Liver disease, Primary sclerosing cholangitis | Phase 2b Data readout | |
MRM-3379 Details Fragile X syndrome (FXS) | Phase 2 Data readout | |
LIVMARLI (Maralixibat) Details Rare diseases, Bile duct disease | Failed Discontinued | |
Volixibat Details Liver disease, Intrahepatic Cholestasis of Pregnancy | Failed Discontinued |
