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Nucana NasdaqCM:NCNA NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer. It applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines. The company is developing medicines to overcome the limitations of nucleoside analogs and generate anti-cancer metabolites in cancer cells. Its pipeline includes NUC-3373, a chemical entity derived from the nucleoside analog 5-fluorouracil that is in Phase 1b/2 study in patients with metastatic colorectal cancer; Phase 2 clinical trial for the second-line treatment of patients with advanced colorectal cancer; and Phase 1 modular clinical trial for patients with advanced solid tumors and lung cancer. The company is also developing NUC-7738, a ProTide transformation of 3'-deoxyadenosine, which is in the Phase 2 part of a Phase 1/2 clinical trial for patients with advanced solid tumors. The company has an assignment, license, and collaboration agreement with Cardiff ProTides Ltd to discover, drug design, and in vitro screen purine and pyrimidine-based nucleosides as potential drug candidates. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017. NuCana plc was incorporated in 1997 and is based in Edinburgh, the United Kingdom.

Location: 3 Lochside Way, Edinburgh, EH12 9DT, United Kingdom | Website: https://www.nucana.com | Industry: Biotechnology | Sector: Healthcare

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52 Wk Range

$ - $

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Avg Volume

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Enterprise Value

14.94M

Cash

3.953M

Avg Qtr Burn

-4.086M

Short % of Float

1.85%

Insider Ownership

0.15%

Institutional Own.

5.61%

Qtr Updated

03/31/25

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Drug & Indication	Stage & Event	Catalyst Date
NUC-3373 (ProTide) combo w/ pembrolizumab Details Solid tumor/s, Cancer, Lung cancer	Phase 1/2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
NUC-7738 (ProTide) +/- pembrolizumab Details Solid tumor/s, Cancer, Melanoma	Phase 1/2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
NUC-3373 (ProTide) combo w/ irinotecan/bevacizumab/oxaliplatin Details Colorectal cancer , Cancer	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Acelarin (NUC-1031) (dFdCTP) Details Cancer, Biliary Tract Cancer	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.