Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1-mutant astrocytoma with safusidenib against placebo. The company was founded in 2018 and is headquartered in New York, New York. Show more

1500 Broadway, New York, NY, 10036, United States

Biotechnology
Healthcare

Market Cap

1.543B

52 Wk Range

$1.54 - $9.75

Previous Close

$4.44

Open

$4.53

Volume

2,686,515

Day Range

$4.44 - $4.63

Enterprise Value

1.071B

Cash

529.2M

Avg Qtr Burn

-29.73M

Insider Ownership

18.79%

Institutional Own.

62.42%

Qtr Updated

12/31/25


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Drug & IndicationStage & EventCatalyst Date
IBTROZI (Taletrectinib) (ROS1 inhibitor) Details
ROS1-Positive Non-small cell lung carcinoma (NSCLC)

Approved

Quarterly sales

IBTROZI (Taletrectinib) Details
ROS1-Positive Early-Stage Non-Small Cell Lung Cancer

Phase 3

Data readout

Safusidenib Details
High-grade Glioma

Phase 3

Data readout

NUV-1511 Details
Advanced solid tumors

Phase 1/2

Update

NUV-868 +olaparib Details
Solid tumor/s, Cancer, Ovarian cancer, Pancreatic cancer, Triple-negative breast cancer , Castration-resistant prostate cancer

Phase 1b

Update

NUV-868 +enzalutamide Details
Solid tumor/s, Cancer, Castration-resistant prostate cancer

Phase 1b

Update

Phase 1

Update

NUV-422 (CDK inhibitor) Details
High-grade Glioma , Solid tumor/s, Cancer, Prostate cancer, Breast cancer, Castration-resistant prostate cancer, Metastatic breast cancer

Failed

Discontinued