Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing therapeutic candidates for oncology. Its lead product candidate is taletrectinib, an ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. The company is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 2 clinical trials; NUV-1511, a drug-drug conjugate for use in chemotherapy agent that suppresses the growth of various advanced solid tumors; and NUV-868, a binding domain 2 bromodomain and extra-terminal inhibitor that inhibits bromodomain-containing protein 4. The company was founded in 2018 and is headquartered in New York, New York. Show more

1500 Broadway, New York, NY, 10036, United States

Biotechnology
Healthcare
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Market Cap

1.872B

52 Wk Range

$1.54 - $9.75

Previous Close

$5.46

Open

$5.52

Volume

4,836,137

Day Range

$5.35 - $5.76

Enterprise Value

719.9M

Cash

549M

Avg Qtr Burn

-52.89M

Insider Ownership

19.05%

Institutional Own.

63.06%

Qtr Updated

09/30/25


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Drug & IndicationStage & EventCatalyst Date
IBTROZI (Taletrectinib) (ROS1 inhibitor) Details
ROS1-Positive Non-small cell lung carcinoma (NSCLC)

Approved

Quarterly sales

IBTROZI (Taletrectinib) Details
ROS1-Positive Early-Stage Non-Small Cell Lung Cancer

Phase 3

Data readout

Safusidenib Details
High-grade Glioma

Phase 3

Data readout

NUV-1511 Details
Advanced solid tumors

Phase 1/2

Update

NUV-868 +enzalutamide Details
Solid tumor/s, Cancer, Castration-resistant prostate cancer

Phase 1b

Update

NUV-868 +olaparib Details
Solid tumor/s, Cancer, Ovarian cancer, Pancreatic cancer, Triple-negative breast cancer , Castration-resistant prostate cancer

Phase 1b

Update

Phase 1

Update

NUV-422 (CDK inhibitor) Details
High-grade Glioma , Solid tumor/s, Cancer, Prostate cancer, Breast cancer, Castration-resistant prostate cancer, Metastatic breast cancer

Failed

Discontinued