Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications. Its lead products include ORKA-001 that targets p19 subunit of interleukin-23, which is in phase 2a trial for the treatment of PsO; and ORKA-002 that targets interleukin-17A and interleukin-17F, which is in phase 2 trial for the treatment of PsO, psoriatic arthritis, and other conditions. The company also develops ORKA-003 for targeting an undisclosed pathway; and ORKA-021, a sequential combination regimen of ORKA-002 and ORKA-001. Oruka Therapeutics, Inc. is headquartered in Menlo Park, California. Show more

855 Oak Grove Avenue, Menlo Park, CA, 94025, United States

Biotechnology

Healthcare

Market Cap

3.498B

52 Wk Range

$8.91 - $70.50

Previous Close

$69.68

Open

$69.95

Volume

1,197,844

Day Range

$67.42 - $71.00

Enterprise Value

3.163B

Cash

337M

Avg Qtr Burn

-22.59M

Insider Ownership

1.64%

Institutional Own.

Qtr Updated

12/31/25

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Drug & Indication	Stage & Event	Catalyst Date
ORKA-001 (IL-23p19 Antibody) Details Psoriasis	Phase 2b Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
ORKA-002 Details Psoriasis	Phase 2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
ORKA-002 (IL-17A/F Antibody) Details Psoriasis	Phase 2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
ORKA-002 (IL-17A/F Antibody) Details Hidradenitis Suppurativa (HS)	Phase 2 Initiation	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
ORKA-001 Details Psoriasis	Phase 2a Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.