Prime Medicine, Inc., a biotechnology company, engages in delivering genetic therapies to address the spectrum of diseases by deploying gene editing technology in the United States. It offers Prime Editing technology comprising a programmable DNA binding domains, such as Cas domains, are typically modified such that they do not cause a double-stranded break in the DNA, as well as a RT domain that copies the edited DNA sequence directly into the target genomic site where the edit is made; and pegRNA which contains a search sequence, also known as a spacer, which provides a target genomic address for the Prime Editor. The company has a research collaboration with Cimeio Therapeutics to develop Prime Edited Shielded-Cell & Immunotherapy Pairs for genetic diseases, acute myeloid leukemia, and myelodysplastic syndrome. Prime Medicine, Inc. was incorporated in 2019 and is headquartered in Cambridge, Massachusetts. Show more
60 First Street, Cambridge, MA, 02141, United States
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Market Cap
602.9M
52 Wk Range
$1.11 - $6.94
Previous Close
$3.34
Open
$3.35
Volume
3,410,416
Day Range
$3.35 - $3.86
Enterprise Value
1.207B
Cash
213.3M
Avg Qtr Burn
-35.04M
Insider Ownership
17.62%
Institutional Own.
64.18%
Qtr Updated
09/30/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
PM359 Details Chronic granulomatous disease | Phase 1/2 Update | |
PM647 (Prime Editing Therapy) Details Alpha-1 Antitrypsin Deficiency | IND Submission | |
PM577 (Prime Editing Therapy) Details Wilson's Disease | IND Submission |
