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Protagonist Therapeutics NASDAQ:PTGX Protagonist Therapeutics is a clinical stage biopharmaceutical company with multiple peptide-based new chemical entities in different stages of development. Rusfertide (PTG-300) is an injectable hepcidin mimetic in a Phase 2 proof-of-concept clinical trial for polycythemia vera, and a separate Phase 2 clinical study for hereditary hemochromatosis. PN-943 is an orally delivered, gut-restricted alpha-4-beta-7 integrin specific antagonist peptide in a 150 patient Phase 2 study for the potential treatment of inflammatory bowel disease, with ulcerative colitis as the initial targeted indication. PTG-200 is an orally delivered, gut-restricted, interleukin-23 receptor specific antagonist peptide in a Phase 2 clinical trial for Crohn's disease. Two additional second-generation oral interleukin-23 receptor antagonist candidates PN-235 and PN-232, are in early stages of clinical development. The Company has developed a proprietary technology platform to discover and develop novel peptide-based therapeutics to address significant unmet medical needs and transform existing treatment paradigms.

Location: | Website: www.protagonist-inc.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing

Market Cap

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52 Wk Range

$ - $

Previous Close

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Open

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Day Range

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Volume

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Avg Volume

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Enterprise Value

2.154B

Cash

564M

Avg Qtr Burn

N/A

Short % of Float

8.06%

Insider Ownership

1.18%

Institutional Own.

Qtr Updated

06/30/24

Drug Pipeline

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Drug & Indication	Stage & Event	Catalyst Date
JNJ-2113 (PN-235) (Oral IL-23 receptor antagonist) Details Psoriasis	Phase 3 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Rusfertide (PTG-300) (Hepcidin Mimetic) Details Blood cancer, Polycythemia vera, Cancer	Phase 3 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
JNJ-2113 (PN-235) (Oral IL-23 receptor antagonist) Details Ulcerative colitis	Phase 2b Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
Rusfertide (PTG-300) (Hepcidin Mimetic) Details Genetic disorder, Rare genetic disease	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
PTG-200 (IL-23R Antagonist) Details Crohns disease, Inflammatory bowel disease, Inflammatory disease	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
PN-943 (α4β7-Integrin Antagonist) Details Inflammatory bowel disease, Inflammatory disease	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.