Rafael Holdings, Inc. primarily engages in holding interests in clinical and early-stage pharmaceutical companies, and medical devices in the United States and Israel. It operates in three segments, Healthcare, Infusion Technology, and Real Estate. The company engages in the development and commercialization of therapies that exploit the metabolic differences between normal cells and cancer cells. Its lead drug candidate is Trappsol Cyclo, which is in phase 3 clinical trial being evaluated for the potential treatment of Niemann-Pick Disease Type C1 ("NPC1"), a rare, fatal and progressive genetic disorder; and CPI-613 (devimistat), a stable analog of normally transient, acylated catalytic intermediates of lipoate, which is in phase II of clinical trial. The company is also involved in developing Promitil, a molecule designed for the targeted delivery of mitomycin-C in a proprietary prodrug form, completed Phase 1A and 1B clinical studies targeting patients with advanced cancers. In addition, it engages in the development of surgical and procedural devices, including orthopedic arthroscopy instrument for Carpal Tunnel syndrome. Rafael Holdings, Inc. was incorporated in 2017 and is headquartered in Newark, New Jersey. Show more

Location: 520 Broad Street, Newark, NJ, 07102, United States | Website: https://www.rafaelholdings.com | Industry: Real Estate Services | Sector: Real Estate


Market Cap

64.2M

52 Wk Range

$1.19 - $3.19

Previous Close

$1.24

Open

$1.27

Volume

69,218

Day Range

$1.20 - $1.28

Enterprise Value

12.12M

Cash

52.77M

Avg Qtr Burn

-4.731M

Insider Ownership

37.74%

Institutional Own.

7.93%

Qtr Updated

07/31/25


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date

Phase 3

Data readout

CPI-613 (devimstat) Details
Blood cancer, Cancer, Leukemia, Lymphoma

Failed

Discontinued

CPI-613 (devimstat) Details
Blood cancer, Cancer, Acute myeloid leukemia

Failed

Discontinued

Failed

Discontinued

CPI-613 (devimstat) Details
Solid tumor/s, Pancreatic cancer, Cancer

Failed

Discontinued

CPI-613 (devimistat) Details
Solid tumor/s, Pancreatic cancer, Cancer

Failed

Discontinued