RIGL - Rigel Pharmaceuticals

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Rigel Pharmaceuticals NasdaqGS:RIGL Rigel Pharmaceuticals, Inc., a biotechnology company, engages in discovering, developing, and providing therapies that enhance the lives of patients with hematologic disorders and cancer. The company's commercialized products include Tavalisse, an oral spleen tyrosine kinase inhibitor for the treatment of adult patients with chronic immune thrombocytopenia; Rezlidhia, a non-intensive monotherapy to treat adult patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation as detected by an FDA-approved test; and GAVRETO, a once daily, small molecule, oral, kinase inhibitor for the treatment of adult patients with metastatic rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC), as well as to treat adult and pediatric patients twelve years of age and older with advanced or metastatic RET fusion-positive thyroid cancer. It also develops R289, an oral interleukin receptor-associated kinases 1 and 4 (IRAK1/4) inhibitor for the treatment of hematology-oncology, autoimmune, and inflammatory diseases, as well as to treat lower-risk myelodysplastic syndrome. In addition, the company has product candidates in clinical development with partners BerGenBio ASA, Eli Lilly and Company, and Daiichi Sankyo. It has strategic development collaboration with The University of Texas MD Anderson Cancer Center for the development of Olutasidenib in AML and other hematologic cancers with IDH1mutations, as well as with collaborative network for neuro-oncology clinical trials to evaluate Olutasidenib in combination with temozolomide in patients with high-grade glioma harboring an IDH1 mutation. Rigel Pharmaceuticals, Inc. was incorporated in 1996 and is headquartered in South San Francisco, California.

Location: 611 Gateway Boulevard, South San Francisco, CA, 94080, United States | Website: https://www.rigel.com | Industry: Biotechnology | Sector: Healthcare


Market Cap

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52 Wk Range

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Volume

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Enterprise Value

373M

Cash

77.1M

Avg Qtr Burn

N/A

Short % of Float

13.90%

Insider Ownership

2.66%

Institutional Own.

79.22%

Qtr Updated

03/31/25


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
REZLIDHIA (Olutasidenib) (FT-2102) Details
Cancer, Acute myeloid leukemia

Approved

Quarterly sales

REZLIDHIA (Olutasidenib) (FT-2102) Details
Glioma, Acute myeloid leukemia, Cancer

Approved

Quarterly sales

GAVRETO (pralsetinib) Details
Non-small cell lung carcinoma

Approved

Quarterly sales

TAVALISSE® (fostamatinib disodium hexahydrate) Details
Adult Chronic Immune Thrombocytopenia (ITP)

Approved

Quarterly sales

Phase 3

Data readout

Phase 2

Initiation

R552 Details
Rheumatoid arthritis, Autoimmune disease

Phase 2a

Data readout

Phase 1/2

Data readout

R289 Details
Lower-risk myeloid dysplastic syndrome

Phase 1b

Data readout

Failed

Discontinued

Failed

Discontinued