Cartesian Therapeutics, Inc., a clinical-stage biotechnology company, provides mRNA cell therapies for the treatment of autoimmune diseases. The company's lead product candidate is Descartes-08, an autologous mRNA chimeric antigen receptor T-cell cell therapy (CAR-T) directed against the B cell maturation antigen (BCMA), which is in Phase 2b clinical trials for the treatment of autoimmune diseases, generalized myasthenia gravis, and systemic lupus erythematosus, as well as rare pediatric disease designation for the treatment of juvenile dermatomyositis. It is also developing Descartes-15, which is in phase 1 trials, an autologous autologous B cell maturation antigen (BCMA) directed mRNA CAR-T to treat patients with multiple myeloma. The company is headquartered in Frederick, Maryland. Show more
7495 New Horizon Way, Frederick, MD, 21703, United States
Market Cap
169.4M
52 Wk Range
$5.60 - $15.57
Previous Close
$6.39
Open
$6.26
Volume
60,432
Day Range
$6.16 - $6.36
Enterprise Value
56.93M
Cash
125.1M
Avg Qtr Burn
-17.71M
Insider Ownership
59.53%
Institutional Own.
28.00%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
SEL-212 (Pegadricase) Details Chronic refractory gout, Arthritis | BLA Submission | |
Descartes-08 Details Myasthenia gravis | Phase 3 Data readout | |
Descartes-08 Details Myositis | Phase 2 Initiation | |
Descartes-08 Details Juvenile dermatomyositis, Juvenile systemic lupus erythematosus (SLE), Juvenile Myasthenia gravis (MG), Anti-neutrophil cytoplasmic antibody associated vasculitis | Phase 1/2 Data readout | |
Descartes-15 Details Multiple myeloma | Phase 1 Data readout | |
Descartes-08 Details Systemic lupus erythematosus | Failed Discontinued | |
SEL-302 (MMA-101 + ImmTOR) Details Genetic disorder, Methylmalonic acidemia | Failed Discontinued |
