Cartesian Therapeutics, Inc., a clinical-stage biotechnology company, provides mRNA cell therapies for the treatment of autoimmune diseases. The company's lead product candidate is Descartes-08, an autologous mRNA chimeric antigen receptor T-cell cell therapy (CAR-T) directed against the B cell maturation antigen (BCMA), which is in Phase 2b clinical trials for the treatment of autoimmune diseases, generalized myasthenia gravis, and systemic lupus erythematosus, as well as rare pediatric disease designation for the treatment of juvenile dermatomyositis. It is also developing Descartes-15, which is in phase 1 trials, an autologous autologous B cell maturation antigen (BCMA) directed mRNA CAR-T to treat patients with multiple myeloma. The company is headquartered in Frederick, Maryland. Show more

7495 New Horizon Way, Frederick, MD, 21703, United States


Market Cap

211.1M

52 Wk Range

$5.98 - $16.79

Previous Close

$8.12

Open

$8.23

Volume

150,702

Day Range

$7.30 - $8.70

Enterprise Value

80.37M

Cash

143.4M

Avg Qtr Burn

-15.6M

Insider Ownership

59.60%

Institutional Own.

19.73%

Qtr Updated

09/30/25


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Drug & IndicationStage & EventCatalyst Date
SEL-212 (Pegadricase) Details
Chronic refractory gout, Arthritis

BLA

Submission

Descartes-08 Details
Myasthenia gravis

Phase 3

Data readout

Phase 2

Initiation

Descartes-08 Details
Juvenile dermatomyositis, Juvenile systemic lupus erythematosus (SLE), Juvenile Myasthenia gravis (MG), Anti-neutrophil cytoplasmic antibody associated vasculitis

Phase 1/2

Data readout

Descartes-15 Details
Multiple myeloma

Phase 1

Data readout

SEL-302 (MMA-101 + ImmTOR) Details
Genetic disorder, Methylmalonic acidemia

Failed

Discontinued

Descartes-08 Details
Systemic lupus erythematosus

Failed

Discontinued