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Repare Therapeutics NasdaqGS:RPTX Repare Therapeutics Inc., a clinical-stage precision oncology company, engages in the discovery and development of therapeutics in Switzerland and the United States. The company uses its proprietary, genome-wide and CRISPR-enabled SNIPRx platform to discover and develop cancer therapies that treat cancers due to mechanisms of genomic instability, including DNA damage repair. It also develops camonsertib (RP-3500), a potent and selective oral small molecule inhibitor of Ataxia-Telangiectasia and Rad3-related protein kinase that is in Phase 1/2 clinical trial for the treatment of solid tumors; and lunresertib (RP-6306), a selective and potent oral small molecule inhibitor of Protein Kinase Membrane-associated tyrosine-and threonine-specific cdc-2 inhibitory kinase that is in Phase 1/2 clinical trial. In addition, the company is developing RP-1664, an oral PLK4 inhibitor in Phase 1 clinical trial to harness the synthetic lethal relationship with TRIM37 amplification or overexpression in solid tumors; and RP-3467, an inhibitor of adenosinetriphosphatase activity on the helicase domain of DNA polymerase theta that is in Phase 1 clinical trial. The company has strategic collaborations with Hoffmann-La Roche Inc., F. HoffmannLa Roche Ltd, Debiopharm International S.A., Bristol-Myers Squibb Company, Ono Pharmaceutical Company Ltd., and New York University. Repare Therapeutics Inc. was incorporated in 2016 and is headquartered in Montreal, Canada.
Location: 7171 Frederick-Banting, Building 2, Montreal, QC, H4S 1Z9, Canada | Website: https://www.reparerx.com | Industry: Biotechnology | Sector: Healthcare
Market Cap
NaN
52 Wk Range
$ - $
Previous Close
$N/A
Open
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Day Range
N/A - N/A
Volume
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Avg Volume
N/A
Enterprise Value
-63.67M
Cash
124.2M
Avg Qtr Burn
-29.38M
Short % of Float
2.43%
Insider Ownership
1.25%
Institutional Own.
76.62%
Qtr Updated
03/31/25
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Lunresertib (RP-6306) +/- Camonsertib (RP-3500) or Debio 0123 Details Ovarian cancer, Endometrial cancer | Phase 3 Initiation | |
Lunresertib (RP-6306) + gemcitabine Details Cancer, Advanced malignancies | Phase 2 Data readout | |
Camonsertib (RP-3500) +/- radiotherapy Details Solid tumor/s, Cancer | Phase 1/2 Update | |
RP-1664 Details Cancer, Neuroblastoma | Phase 1/2 Initiation | |
Lunresertib (RP-6306) + gemcitabine Details Solid tumor/s, Cancer | Phase 1 Data readout | |
RP-1664 Details Cancer, Solid tumor/s | Phase 1 Data readout | |
RP-3467 +/- olaparib Details Solid tumor/s, Cancer | Phase 1 Data readout | |
Lunresertib (RP-6306) + FOLFIRI Details Solid tumor/s, Cancer | Phase 1 Update |