Revolution Medicines, Inc., a clinical-stage precision oncology company, develops novel targeted therapies for RAS-addicted cancers. The company's research and development pipeline consist of RAS(ON) inhibitors that binds RAS variants to be used as monotherapy in combination with other RAS(ON) inhibitors and/or in combination with RAS companion inhibitors or other therapeutic agents, and RAS companion inhibitors to suppress cooperating targets and pathways that sustain RAS-addicted cancers. Its RAS(ON) inhibitors include daraxonrasib (RMC-6236), elironrasib G12C (RMC-6291) which is in early clinical development for the treatment of solid tumors, and zoldonrasib G12D (RMC-9805), which are in phase 3 registrational trial evaluating the combination of daraxonrasib with zoldonrasib in patients with 1L PDAC; and development candidates comprise RMC-5127 (G12V) which is in clinical trial, RMC-0708 (Q61H), that is in clinical trial; and RMC-8839 (G13C). Revolution Medicines, Inc. was incorporated in 2014 and is headquartered in Redwood City, California. Show more

700 Saginaw Drive, Redwood City, CA, 94063, United States

Biotechnology
Healthcare

Market Cap

18.8B

52 Wk Range

$29.17 - $124.49

Previous Close

$94.86

Open

$96.60

Volume

1,542,284

Day Range

$96.60 - $99.64

Enterprise Value

16.93B

Cash

2.026B

Avg Qtr Burn

-274.2M

Insider Ownership

1.89%

Institutional Own.

-

Qtr Updated

12/31/25


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Drug & IndicationStage & EventCatalyst Date
Daraxonrasib (RMC-6236) (RAS(ON) Inhibitor) Details
Resectable Pancreatic Ductal Adenocarcinoma

Phase 3

Data readout

Phase 3

Data readout

RMC-6236 Details
RAS mutant Non-small cell lung carcinoma

Phase 3

Data readout

Daraxonrasib (RMC-6236) Details
Pancreatic ductal adenocarcinoma , Cancer

Phase 3

Data readout

RMC-6236+ pembrolizumab Details
Solid tumor/s, Non-small cell lung carcinoma, Cancer

Phase 3

Initiation

Daraxonrasib (RMC-6236) Details
Pancreatic ductal adenocarcinoma , Cancer

Phase 3

Initiation

Daraxonrasib (RMC-6236) Details
Pancreatic ductal adenocarcinoma , Cancer

Phase 3

Initiation

RMC-4630 + sotorasib Details
Non-small cell lung carcinoma, Cancer

Phase 1b

Data readout

RMC-5552 (mTORC1 inhibitor) Details
Breast cancer, Renal cell carcinoma, Glioblastoma, Solid tumor/s, Cancer

Phase 1b

Data readout

RMC-5127 Details
no known indication

Phase 1

Data readout

RMC-6291 (KRASG12C) Details
Solid tumor/s, Cancer

Phase 1

Data readout

RMC-6291+ pembrolizumab Details
Solid tumor/s, Non-small cell lung carcinoma, Cancer

Phase 1

Data readout

RMC-6236 + RMC-6291 Details
Solid tumor/s, Cancer

Phase 1

Update

RMC-9805 (KRASG12D) Details
Colorectal cancer , Pancreatic cancer, Non-small cell lung carcinoma, Cancer

Phase 1

Update

RMC-6236 (RASMULTI) Details
Solid tumor/s, Pancreatic cancer, Non-small cell lung carcinoma, Cancer

Phase 1

Update

RMC-4630 (SHP2 inhibitor) Details
Colorectal cancer , Solid tumor/s, Cancer

Failed

Discontinued