Revolution Medicines, Inc., a clinical-stage precision oncology company, develops novel targeted therapies for RAS-addicted cancers. The company's research and development pipeline consist of RAS(ON) inhibitors that binds RAS variants to be used as monotherapy in combination with other RAS(ON) inhibitors and/or in combination with RAS companion inhibitors or other therapeutic agents, and RAS companion inhibitors to suppress cooperating targets and pathways that sustain RAS-addicted cancers. Its RAS(ON) inhibitors include daraxonrasib (RMC-6236), elironrasib G12C (RMC-6291), and zoldonrasib G12D (RMC-9805), which are in phase 1 clinical trial; and development candidates comprise RMC-5127 (G12V), RMC-0708 (Q61H), and RMC-8839 (G13C). The company's RAS companion inhibitors include RMC-4630 that is in phase 2 clinical trial; RMC-5552, a selective inhibitor of mTORC1 signaling in tumors, which is in phase 1 clinical trial; and RMC-5845 that targets SOS1. Revolution Medicines, Inc. was incorporated in 2014 and is headquartered in Redwood City, California. Show more

700 Saginaw Drive, Redwood City, CA, 94063, United States

Biotechnology
Healthcare
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Market Cap

20.05B

52 Wk Range

$29.17 - $124.49

Previous Close

$103.69

Open

$103.69

Volume

1,837,539

Day Range

$103.28 - $105.29

Enterprise Value

6.538B

Cash

1.932B

Avg Qtr Burn

-207.3M

Insider Ownership

2.04%

Institutional Own.

-

Qtr Updated

09/30/25


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Drug & IndicationStage & EventCatalyst Date
Daraxonrasib (RMC-6236) (RAS(ON) Inhibitor) Details
Resectable Pancreatic Ductal Adenocarcinoma

Phase 3

Data readout

RMC-6236 Details
RAS mutant Non-small cell lung carcinoma

Phase 3

Data readout

Phase 3

Data readout

Daraxonrasib (RMC-6236) Details
Pancreatic ductal adenocarcinoma , Cancer

Phase 3

Data readout

RMC-6236+ pembrolizumab Details
Solid tumor/s, Non-small cell lung carcinoma, Cancer

Phase 3

Initiation

Daraxonrasib (RMC-6236) Details
Pancreatic ductal adenocarcinoma , Cancer

Phase 3

Initiation

Daraxonrasib (RMC-6236) Details
Pancreatic ductal adenocarcinoma , Cancer

Phase 3

Initiation

RMC-4630 + sotorasib Details
Non-small cell lung carcinoma, Cancer

Phase 1b

Data readout

RMC-5552 (mTORC1 inhibitor) Details
Breast cancer, Renal cell carcinoma, Glioblastoma, Solid tumor/s, Cancer

Phase 1b

Data readout

RMC-5127 Details
no known indication

Phase 1

Data readout

RMC-6291 (KRASG12C) Details
Solid tumor/s, Cancer

Phase 1

Data readout

RMC-6291+ pembrolizumab Details
Solid tumor/s, Non-small cell lung carcinoma, Cancer

Phase 1

Data readout

RMC-6236 (RASMULTI) Details
Solid tumor/s, Pancreatic cancer, Non-small cell lung carcinoma, Cancer

Phase 1

Update

RMC-6236 + RMC-6291 Details
Solid tumor/s, Cancer

Phase 1

Update

RMC-9805 (KRASG12D) Details
Colorectal cancer , Pancreatic cancer, Non-small cell lung carcinoma, Cancer

Phase 1

Update

RMC-4630 (SHP2 inhibitor) Details
Colorectal cancer , Solid tumor/s, Cancer

Failed

Discontinued