Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts. Show more
675 Massachusetts Avenue, Cambridge, MA, 02139, United States
Market Cap
158.6M
52 Wk Range
$0.57 - $3.22
Previous Close
$2.80
Open
$2.82
Volume
346,529
Day Range
$2.74 - $2.82
Enterprise Value
121.5M
Cash
40.27M
Avg Qtr Burn
-8.351M
Insider Ownership
22.56%
Institutional Own.
16.93%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Tebipenem HBr (previously SPR994): oral carbapenem Details Bacterial infection, Urinary tract infection | PDUFA Approval decision | |
SPR720 Details Bacterial infection, Lung disease | Failed Discontinued |
