Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, siRNA platform, gene therapy, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping; AMONDYS 45 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 45 skipping; and ELEVIDYS, an AAV-based gene therapy, which is contraindicated in patients with any deletion in exon 8 and/or exon 9 in the Duchenne gene. The company also develops SRP-9003, a gene therapy program for the treatment of LGMD2E; SRP-1001 to selectively target and knockdown DUX4 using RNAi in Phase 1/2a clinical trials; and SRP-1003 for reduction of expression of the DMPK gene in Phase 1/2a clinical trials. It has collaboration and license agreements with F. Hoffman-La Roche Ltd; Arrowhead Pharmaceuticals, Inc.; University of Western Australia; Nationwide Children's Hospital; Hansa Biopharma; and Duke University. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts. Show more

215 First Street, Cambridge, MA, 02142, United States

Biotechnology
Healthcare

Market Cap

2.097B

52 Wk Range

$10.42 - $76.67

Previous Close

$21.68

Open

$21.67

Volume

4,609,422

Day Range

$19.72 - $21.67

Enterprise Value

1.853B

Cash

939.7M

Avg Qtr Burn

N/A

Insider Ownership

5.15%

Institutional Own.

90.18%

Qtr Updated

12/31/25


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Drug & IndicationStage & EventCatalyst Date

Approved

Update

ELEVIDYS (SRP-9001) Details
Duchenne muscular dystrophy

Approved

Update

Approved

Quarterly sales

VYONDYS 53 (golodirsen) Details
Duchenne muscular dystrophy

Approved

Quarterly sales

EXONDYS 51 (eteplirsen) Details
Duchenne muscular dystrophy

Approved

Quarterly sales

Phase 3

Update

SRP-9003 Details
Limb-Girdle Muscular Dystrophy (LGMD type 2E/R4)

Phase 3

Update

SRP-5051 (vesleteplirsen) Details
Duchenne muscular dystrophy

Phase 2

Update

SRP-1003 Details
Myotonic dystrophy type 1 (DM1)

Phase 1/2

Update

SRP-1001 Details
Facioscapulohumeral muscular dystrophy (FSHD)

Phase 1/2

Update

SRP-1004 Details
Spinocerebellar ataxia type 2 (SCA2)

Phase 1

Update

SRP-1005 Details
Huntington’s Disease (HD)

Phase 1

Initiation

SRP-6004 Details
Dysferlinopathy, Limb-Girdle Muscular Dystrophy

Failed

Discontinued

SRP-9005 Details
Limb-Girdle Muscular Dystrophy (LGMD type 2C/R5)

Failed

Discontinued

SRP-9004 Details
Limb-Girdle Muscular Dystrophy (LGMD type 2D/R3)

Failed

Discontinued