Shattuck Labs, Inc., a clinical-stage biotechnology company, engages in the development of antibodies for the treatment of inflammatory and immune-mediated diseases in the United States. The company develops SL-325, a death receptor 3 blocking monoclonal antibody, which is in Phase I clinical trial for the treatment of tumor necrosis factor like ligand 1A; and SL-425, a half-life extended version of SL-325, which is under IND-enabling chronic good laboratory practices toxicity study. It is also involved in the development of various preclinical DR3-based bispecific antibodies for the treatment of patients with inflammatory bowel disease or other immune-mediated indications; and TRIM7, an oncology-focused program. The company was incorporated in 2016 and is headquartered in Austin, Texas. Show more

500 West 5th Street, Austin, TX, 78701, United States

Biotechnology
Healthcare

Market Cap

379M

52 Wk Range

$0.69 - $6.25

Previous Close

$5.99

Open

$6.00

Volume

505,587

Day Range

$5.94 - $6.26

Enterprise Value

295.2M

Cash

86.13M

Avg Qtr Burn

-8.929M

Insider Ownership

9.76%

Institutional Own.

67.35%

Qtr Updated

09/30/25


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Drug & IndicationStage & EventCatalyst Date
SL-325 Details
Inflammatory Bowel Disease (IBD)

Phase 1

Data readout

Failed

Discontinued

SL-172154 Details
Ovarian cancer, Cancer

Failed

Discontinued

SL-172154 +/- azacitidine Details
Cancer, Myelodysplastic syndrome, Acute myeloid leukemia

Failed

Discontinued

SL-279252 Details
Solid tumor/s, Cancer, Lymphoma

Failed

Discontinued

Failed

Discontinued

SL-172154 Details
Cancer, Head and neck squamous cell carcinoma, Cutaneous squamous cell carcinoma

Failed

Discontinued

SL-172154 Details
Ovarian cancer, Cancer

Failed

Discontinued