SWTX - SpringWorks Therapeutics Inc

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SpringWorks Therapeutics Inc NasdaqGS:SWTX SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. It offers OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor for the treatment of desmoid tumors; and GOMEKLI (mirdametinib), an oral small molecule inhibitor of MEK1 and MEK2 for the treatment of adult and pediatric patients two years of age and older with neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN). The company also develops Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer; and mirdametinib for the treatment of solid tumors harboring other MAPK aberrations, including for the treatment of pediatric and young adult patients with low-grade gliomas that is in Phase 1/2 clinical trial. In addition, its products under development include Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has license agreements with Pfizer Inc. for nirogacestat and mirdametinib; and Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain. SpringWorks Therapeutics, Inc. was founded in 2017 and is headquartered in Stamford, Connecticut.

Location: 100 Washington Boulevard, Stamford, CT, 06902, United States | Website: https://www.springworkstx.com | Industry: Biotechnology | Sector: Healthcare


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52 Wk Range

$ - $

Previous Close

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Avg Volume

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Enterprise Value

3.236B

Cash

287.9M

Avg Qtr Burn

-41.36M

Short % of Float

8.03%

Insider Ownership

1.28%

Institutional Own.

87.64%

Qtr Updated

03/31/25


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date

Approved

Quarterly sales

GOMEKLI™ (mirdametinib) Details
NF1-associated Plexiform Neurofibromas, Cancer

Approved

Quarterly sales

Nirogacestat Details
Cancer, Ovarian cancer, recurrent ovarian granulosa cell tumors

Phase 2

Data readout

Phase 1/2

Data readout

Phase 1/2

Data readout

Phase 1/2

Data readout

Phase 1/2

Data readout

Phase 1/2

Update

Nirogacestat + teclistamab Details
Multiple myeloma, Cancer

Phase 1b

Data readout

Phase 1b

Data readout

Brimarafenib (BGB-3245) + panitumumab Details
Cancer, Colorectal cancer , Pancreatic cancer

Phase 1b

Data readout

Phase 1b

Data readout

Phase 1a

Data readout

IND

Submission