Tectonic Therapeutic, Inc., a biotechnology company, focuses on the discovery and development of therapeutic proteins and antibodies to modulate the activity of G protein coupled receptors (GPCRs). It develops GEODe technology platform to enable the discovery and development of GPCR-targeted biologic medicines. The company's lead product is TX45, a Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone, and relaxin. It is also developing TX2100 for the treatment of hereditary hemorrhagic telangiectasia; GPCR modulator bispecific for treating fibrosis; and other GPCR modulators. The company is headquartered in Watertown, Massachusetts. Show more

490 Arsenal Way, Watertown, MA, 02472, United States

https://tectonictx.com

Biotechnology

Healthcare

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Market Cap

640.7M

52 Wk Range

$13.70 - $36.03

Previous Close

$34.12

Open

$34.68

Volume

270,272

Day Range

$31.39 - $34.68

Enterprise Value

387.2M

Cash

253.8M

Avg Qtr Burn

-14.46M

Insider Ownership

39.06%

Institutional Own.

80.37%

Qtr Updated

12/31/25

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Drug & Indication	Stage & Event	Catalyst Date
TX45 Details Pulmonary Hypertension (PH) associated with Interstitial Lung Disease (ILD)	Phase 2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
TX45 Details Pulmonary hypertension in Heart failure with preserved Ejection Fraction (PH-HFpEF)	Phase 2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
TX45 Details Pulmonary hypertension in Heart failure with preserved Ejection Fraction (PH-HFpEF)	Phase 2 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
TX45 (RXFP1 Agonist) Details Pulmonary Hypertension In Heart Failure With Reduced Ejection Fraction (PH-HFrEF)	Phase 1b Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
TX2100 Details Hereditary Hemorrhagic Telangiectasia (HHT)	Phase 1a Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.