Tectonic Therapeutic, Inc., a biotechnology company, focuses on the discovery and development of therapeutic proteins and antibodies to modulate the activity of G protein coupled receptors (GPCRs). It develops GEODe technology platform to enable the discovery and development of GPCR-targeted biologic medicines. The company's lead product is TX45, a Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone, and relaxin. It is also developing TX2100 for the treatment of hereditary hemorrhagic telangiectasia; GPCR modulator bispecific for treating fibrosis; and other GPCR modulators. The company is headquartered in Watertown, Massachusetts. Show more

490 Arsenal Way, Watertown, MA, 02472, United States

Biotechnology
Healthcare

Market Cap

577.9M

52 Wk Range

$13.70 - $36.03

Previous Close

$30.78

Open

$30.28

Volume

163,055

Day Range

$30.05 - $31.80

Enterprise Value

324.9M

Cash

253.8M

Avg Qtr Burn

-14.46M

Insider Ownership

38.81%

Institutional Own.

80.35%

Qtr Updated

12/31/25


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Drug & IndicationStage & EventCatalyst Date
TX45 Details
Pulmonary Hypertension (PH) associated with Interstitial Lung Disease (ILD)

Phase 2

Data readout

TX45 Details
Pulmonary hypertension in Heart failure with preserved Ejection Fraction (PH-HFpEF)

Phase 2

Data readout

TX45 Details
Pulmonary hypertension in Heart failure with preserved Ejection Fraction (PH-HFpEF)

Phase 2

Data readout

TX45 (RXFP1 Agonist) Details
Pulmonary Hypertension In Heart Failure With Reduced Ejection Fraction (PH-HFrEF)

Phase 1b

Data readout

TX2100 Details
Hereditary Hemorrhagic Telangiectasia (HHT)

Phase 1a

Data readout