TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. It provides BRIUMVI, an anti-CD20 monoclonal antibody for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. The company's development pipeline comprises Ublituximab IV, glycoengineered anti-CD20 mAb for the treatment of relapsing MS; TG-1701 is an orally available and covalently bound Bruton's tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening; and TG-1801, a bispecific CD47 and CD19 antibody. Its research pipeline includes various investigational medicines. The company has license agreements with LFB Biotechnologies S.A.S; GTC Biotherapeutics; LFB/GTC LLC; Ildong Pharmaceutical Co. Ltd.; Rhizen Pharmaceuticals, S A. for the development and commercialization of umbralisib; Jiangsu Hengrui Medicine Co.; and Novimmune SA, as well as collaboration agreement with Checkpoint Therapeutics, Inc. for the development and commercialization of anti-PD-L1 and anti-GITR antibody research programs in the field of hematological malignancies. The company was incorporated in 1993 and is based in Morrisville, North Carolina. Show more

3020 Carrington Mill Blvd., Morrisville, NC, 27560, United States

Biotechnology
Healthcare
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Market Cap

4.853B

52 Wk Range

$25.28 - $46.48

Previous Close

$30.57

Open

$30.56

Volume

1,259,759

Day Range

$30.15 - $31.08

Enterprise Value

5.819B

Cash

131.6M

Avg Qtr Burn

-23.15M

Insider Ownership

7.54%

Institutional Own.

66.34%

Qtr Updated

09/30/25


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Drug & IndicationStage & EventCatalyst Date

Approved

Quarterly sales

Phase 3

Data readout

Azercabtagene zapreleucel (azer-cel) Details
Primary progressive multiple sclerosis

Phase 1

Data readout

TG-1801 Details
B-cell malignancies, Cancer, B-cell lymphoma

Phase 1

Update

TG-1701 (BTK inhibitor) Details
Chronic lymphocytic leukemia, Cancer

Phase 1

Update

Umbralisib (PI3K-delta & CK1-epsilon inhibitor) + Ublituximab (CD20) Details
R/R CLL (Relapsed/Refractory Chronic Lymphocytic Leukemia)

Failed

Discontinued

Failed

Discontinued