TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. It provides BRIUMVI, an anti-CD20 monoclonal antibody for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. The company's development pipeline comprises Ublituximab IV, glycoengineered anti-CD20 mAb for the treatment of relapsing MS; TG-1701 is an orally available and covalently bound Bruton's tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening; and TG-1801, a bispecific CD47 and CD19 antibody. Its research pipeline includes various investigational medicines. The company has license agreements with LFB Biotechnologies S.A.S; GTC Biotherapeutics; LFB/GTC LLC; Ildong Pharmaceutical Co. Ltd.; Rhizen Pharmaceuticals, S A. for the development and commercialization of umbralisib; Jiangsu Hengrui Medicine Co.; and Novimmune SA, as well as collaboration agreement with Checkpoint Therapeutics, Inc. for the development and commercialization of anti-PD-L1 and anti-GITR antibody research programs in the field of hematological malignancies. The company was incorporated in 1993 and is based in Morrisville, North Carolina. Show more
Location: 3020 Carrington Mill Blvd., Morrisville, NC, 27560, United States | Website: https://www.tgtherapeutics.com | Industry: Biotechnology | Sector: Healthcare
Market Cap
5.398B
52 Wk Range
$22.92 - $46.48
Previous Close
$34.02
Open
$34.01
Volume
3,256,396
Day Range
$33.81 - $36.65
Enterprise Value
5.819B
Cash
251.9M
Avg Qtr Burn
-14.78M
Insider Ownership
9.73%
Institutional Own.
64.24%
Qtr Updated
06/30/25
Drug Pipeline
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| Drug & Indication | Stage & Event | Catalyst Date | 
|---|---|---|
| BRIUMVI (ublituximab-xiiy) (CD20)  Details  Multiple sclerosis | Approved Quarterly sales | |
| BRIUMVI (ublituximab-xiiy) subcutaneous Details  Multiple sclerosis | Phase 3 Data readout | |
| Azercabtagene zapreleucel (azer-cel) Details  Primary progressive multiple sclerosis | Phase 1 Data readout | |
| TG-1701 (BTK inhibitor) Details  Chronic lymphocytic leukemia, Cancer | Phase 1 Update | |
| TG-1801 Details  B-cell malignancies, Cancer, B-cell lymphoma | Phase 1 Update | |
| Umbralisib (PI3K-delta & CK1-epsilon inhibitor) + Ublituximab (CD20) Details  R/R CLL (Relapsed/Refractory Chronic Lymphocytic Leukemia) | Failed Discontinued | |
| UKONIQ® (Umbralisib) (PI3K-delta & CK1-epsilon inhibitor) Details  FL (Follicular Lymphoma)  | Failed Discontinued | 
