Vanda Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of therapies to address high unmet medical needs worldwide. The company's commercial portfolio includes Fanapt for the acute treatment of manic or mixed episodes associated with bipolar I disorder and the treatment of schizophrenia; HETLIOZ to treat non-24-hour sleep-wake disorders and nighttime sleep disturbances; PONVORY to treat relapsing forms of multiple sclerosis; and NEREUSTM for preventing vomiting induced by motion. It also develops Fanapt (iloperidone), a long acting injectable (LAI) formulation for the treatment of schizophrenia and hypertension; BysantiTM (milsaperidone), for the acute treatment of manic or mixed episodes associated with bipolar I disorder, and for the treatment of schizophrenia and major depressive disorder; HETLIOZ (tasimelteon) to treat jet lag disorder, insomnia, pediatric insomnia, delayed sleep phase disorder, and pediatric Non-24; PONVORY (ponesimod) to treat psoriasis and ulcerative colitis; and NEREUSTM (tradipitant) for prevention of vomiting induced by GLP-1 receptor agonists, as well as treatment of gastroparesis and atopic dermatitis. In addition, the company's products include Imsidolimab, an IL-36R antagonist to treat generalized pustular psoriasis; VTR-297, for the treatment of hematologic malignancies and onychomycosis, and several oncology indications; and VQW-765, small molecule alpha-7 nicotinic acetylcholine receptor partial agonist for the treatment of social/performance anxiety and psychiatric disorders. Further, it develops cystic fibrosis transmembrane conductance regulator activators and inhibitors; and antisense oligonucleotide molecules. The company was incorporated in 2002 and is headquartered in Washington, the District of Columbia. Show more
2200 Pennsylvania Avenue NW, Washington, DC, 20037, United States
Market Cap
481.7M
52 Wk Range
$3.81 - $9.60
Previous Close
$8.15
Open
$8.04
Volume
7,506,538
Day Range
$7.72 - $8.55
Enterprise Value
238.4M
Cash
263.8M
Avg Qtr Burn
-29.42M
Insider Ownership
8.94%
Institutional Own.
72.43%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Bysanti™ (milsaperidone) Details Bipolar I manic and mixed episodes and schizophrenia | Approved Quarterly sales | |
NEREUS (tradipitant) Details Motion sickness | Approved Quarterly sales | |
Fanapt® (iloperidone) Details Mental health, Bipolar depression, Bipolar disease | Approved Quarterly sales | |
HETLIOZ® (tasimelteon) Details SMS (Smith-Magenis Syndrome) | Approved Quarterly sales | |
Fanapt® (iloperidone) Details Schizophrenia and PDP (Parkinson's disease psychosis) | Approved Quarterly sales | |
HETLIOZ® (tasimelteon) Details Non-24-Hour Sleep-Wake Disorder (Non-24) | Approved Quarterly sales | |
PONVORY® (ponesimod) Details Multiple sclerosis | Approved Quarterly sales | |
Imsidolimab (IL-36 Inhibitor) Details Generalized Pustular Psoriasis | BLA Submission | |
Imsidolimab (IL-36 Inhibitor) Details Generalized Pustular Psoriasis | BLA Submission | |
HETLIOZ® (tasimelteon) Details Insomnia | sNDA Resubmission | |
HETLIOZ® (tasimelteon) Details Jet Lag | sNDA Resubmission | |
Tradipitant Details Gastroparesis | NDA Resubmission | |
Fanapt/Iloperidone LAI (D2 Antagonist) Details Schizophrenia, Relapse Prevention | Phase 3 Data readout | |
VQW-765 Details Social Anxiety Disorder | Phase 3 Data readout | |
Bysanti™ (milsaperidone) Details Mental Health, Major depressive disorder | Phase 3 Data readout | |
Tradipitant Details Nausea and Vomiting in Obesity (After GLP-1R Agonist Use) | Phase 3 Initiation | |
VSJ-110 Details Dry eye disease | Phase 2 Data readout | |
Fanapt/Iloperidone LAI (D2 Antagonist) Details Treatment-Resistant Hypertension | Phase 2 Data readout | |
Trichostatin A (VTR-297) Details Onychomycosis, Fungal infections | Phase 1 Data readout | |
VCA-894A Details Charcot-Marie-Tooth disease, axonal, type 2S , Neuropathy | Phase 1 Data readout | |
Trichostatin A (VTR-297) Details Leukemia, Multiple myeloma, Lymphoma | Failed Discontinued | |
Tradipitant Details Atopic pruritus , Atopic dermatitis | Failed Discontinued | |
Failed Discontinued |
