X4 Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases of the immune system. It offers XOLREMDI, an orally bioavailable selective antagonist of chemokine receptor C-X-C chemokine receptor type 4 (CXCR4) for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome. The company also develops mavorixafor that is in Phase 3 4WARD clinical trial to evaluate the efficacy, safety, and tolerability of oral, once-daily mavorixafor with or without stable doses of G-CSF in people with congenital, acquired primary autoimmune, or idiopathic CN who are experiencing recurrent and/or serious infections. It has a license agreement with Abbisko Therapeutics Co Ltd. to develop, manufacture, and commercialize mavorixafor in combination with checkpoint inhibitors or other agents in oncology indications; and with Norgine to develop, manufacture, and commercialize mavorixafor in Europe, Australia, and New Zealand. The company is headquartered in Boston, Massachusetts. Show more
61 North Beacon Street, Boston, MA, 02134, United States
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Market Cap
276.3M
52 Wk Range
$1.35 - $14.70
Previous Close
$3.16
Open
$3.17
Volume
221,938
Day Range
$3.14 - $3.43
Enterprise Value
93.2M
Cash
122.2M
Avg Qtr Burn
-27.82M
Insider Ownership
1.15%
Institutional Own.
93.89%
Qtr Updated
09/30/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Mavorixafor (CXCR4 inhibitor) Details WHIM Syndrome | Approved Quarterly sales | |
Mavorixafor (CXCR4 inhibitor) Details Severe Congenital Neutropenia | Phase 3 Data readout | |
Mavorixafor (CXCR4 inhibitor) Details Chronic Neutropenia | Phase 2 Update | |
Mavorixafor (CXCR4 inhibitor) + ibrutinib Details Waldenstrom macroglobulinemia | Failed Discontinued | |
Mavorixafor (CXCR4 inhibitor) Details Renal cell carcinoma, Cancer | Failed Discontinued |
