
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Zymeworks NASDAQ:ZYME Zymeworks is a clinical-stage biopharmaceutical company dedicated to the development of next-generation multifunctional biotherapeutics. Zymeworks' suite of therapeutic platforms and its fully integrated drug development engine enable precise engineering of highly differentiated product candidates. Zymeworks' lead clinical candidate, zanidatamab (ZW25), is a novel Azymetric™ bispecific antibody which has been granted Breakthrough Therapy designation by the FDA and is currently enrolling in a pivotal clinical trial for refractory HER2-amplified biliary tract cancer (HERIZON-BTC-01) as well as several Phase 2 clinical trials for HER2-expressing gastroesophageal and breast cancers. Zymeworks' second clinical candidate, ZW49, is a novel bispecific HER2-targeting antibody-drug conjugate currently in Phase 1 clinical development and combines the unique design and antibody framework of zanidatamab with Zymeworks' proprietary ZymeLink™ linker and cytotoxin. Zymeworks is also advancing a deep preclinical pipeline in oncology (including immuno-oncology agents) and other therapeutic areas. In addition, its therapeutic platforms are being leveraged through strategic partnerships with nine biopharmaceutical companies.
Location: 1385 8th Ave W Suite 540, British Columbia, V6H 3V9, Canada | Website: www.zymeworks.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing
Market Cap
NaN
52 Wk Range
$ - $
Previous Close
$N/A
Open
$N/A
Day Range
N/A - N/A
Volume
N/A
Avg Volume
N/A
Enterprise Value
714.2M
Cash
297.2M
Avg Qtr Burn
-13.65M
Short % of Float
10.96%
Insider Ownership
0.17%
Institutional Own.
-
Qtr Updated
09/30/24
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
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Ziihera® (zanidatamab-hrii) Details Cancer, Solid tumor/s, Biliary Tract Cancer | Approved Quarterly sales | |
Zanidatamab + Chemo/trastuzumab Details Breast cancer, Cancer, HER2-expressing cancers | Phase 3 Initiation | |
Zanidatamab (HER2) + chemotherapy + tislelizumab Details Cancer, Gastroesophageal adenocarcinomas, Cholangiocarcinoma | Phase 2 Update | |
Zanidatamab zovodotin (ZW49) Details HER2-expressing cancers, Cancer, Non-small cell lung carcinoma | Phase 2 Update | |
Zanidatamab (HER2) + docetaxel Details Cancer, Breast cancer | Phase 1/2 Data readout | |
ZW191 Details Cancer, Solid tumor/s | Phase 1 Data readout | |
ZW171 Details Cancer, Mesothelin-expressing solid tumors | Phase 1 Data readout | |
ZW251 (GPC3 ADC) Details Cancer | IND Submission | |
ZW220 (NaPi2b ADC) Details Cancer | IND Submission |