Alector, Inc., a clinical stage biotechnology company, develops therapies to counteract the progression of neurodegeneration in the United States. Its pipeline includes Nivisnebart, an investigational human recombinant monoclonal antibody for treating prevalent neurodegenerative diseases; AL137, an anti-amyloid beta antibody paired in preclinical development for the potential treatment of Alzheimer's disease; and AL050, a GCase enzyme replacement therapy in preclinical development for the potential treatment of Parkinson's disease and Lewy body dementia in patients having GBA1 gene mutations. The company also develops its preclinical and research pipeline comprising AL064, a tau siRNA for Alzheimer's disease and other tauopathies; ADP062-ABC, an alpha-synuclein siRNA for Parkinson's disease; and ADP065-ABC, an NLRP3 siRNA for neurodegenerative conditions. It has a strategic collaboration agreement with GlaxoSmithKline plc for the development and commercialization of progranulin-elevating monoclonal antibodies, including Latozinemab and Nivisnebart. The company was founded in 2013 and is headquartered in South San Francisco, California. Show more
131 Oyster Point Boulevard, South San Francisco, CA, 94080, United States
Market Cap
242.8M
52 Wk Range
$0.87 - $3.40
Previous Close
$2.20
Open
$2.29
Volume
372,318
Day Range
$2.19 - $2.29
Enterprise Value
23.01M
Cash
256M
Avg Qtr Burn
-41.69M
Insider Ownership
9.92%
Institutional Own.
80.80%
Qtr Updated
12/31/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
AL101 (GSK4527226) (Progranulin) Details Parkinson's disease, Alzheimer's disease, Neurological disorder | Phase 2 Interim update | |
ADP065-ABC (NLRP3 Targeting SiRNA) Details Neurodegenerative diseases | IND Submission | |
ADP062-ABC (Alpha-Synuclein SiRNA) Details Parkinson's disease, Lewy body dementia | IND Submission | |
AL050 (GCase Enzyme Replacement) Details Parkinson's disease, Lewy body dementia | IND Submission | |
AL137 (Amyloid Beta Antibody) Details Alzheimer's disease | IND Submission | |
ADP064-ABC (Tau Targeting SiRNA) Details Alzheimer's disease, Tauopathies | IND Submission | |
AL002 (TREM 2) Details Alzheimer's disease | Failed Discontinued | |
Latozinemab (AL001) (progranulin) Details Frontotemporal dementia with a granulin mutation, Dementia | Failed Discontinued | |
AL003 (SIGLEC 3) Details Alzheimer's disease | Failed Discontinued |
