Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops medicines for treating inflammatory-related diseases. The company's lead candidate is ANX005, an investigational full-length monoclonal antibody, which is in Phase 3 clinical trial for the treatment of patients with guillain-barré syndrome; completed Phase II clinical trial for treating Huntington's disease; and in Phase 2a clinical trial for the treatment of amyotrophic lateral sclerosis. The company is also developing ANX007, an antigen-binding fragment (Fab) that is in Phase 3 program for the treatment of patients with geographic atrophy; and ANX1502, a novel oral small molecule inhibitor, which is in Phase 1 clinical trials for autoimmune indications. In addition, it develops ANX009, a C1q-blocking Fab that is in Phase I clinical trial for treating patients with lupus nephritis. The company was incorporated in 2011 and is headquartered in Brisbane, California. Show more

1400 Sierra Point Parkway, Brisbane, CA, 94005, United States

Biotechnology
Healthcare
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Market Cap

728.9M

52 Wk Range

$1.28 - $7.18

Previous Close

$4.89

Open

$4.93

Volume

2,674,678

Day Range

$4.89 - $5.05

Enterprise Value

142.4M

Cash

188.7M

Avg Qtr Burn

-52.3M

Insider Ownership

0.32%

Institutional Own.

-

Qtr Updated

09/30/25


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Drug & IndicationStage & EventCatalyst Date

BLA

Submission

Vonaprument (ANX007) (IVT) Details
Dry age-related macular degeneration (AMD) with geographic atrophy (GA)

Phase 3

Data readout

Tanruprubart (ANX005) (IV) Details
Huntington's disease, Brain disease

Phase 3

Initiation

Tanruprubart (ANX005) (IV) Details
Amyotrophic lateral sclerosis, Neurodegenerative disease

Phase 2a

Update

ANX009 Details
Lupus nephritis

Phase 1b

Update

ANX105 Details
Autoimmune disease, Neurodegenerative disease

Phase 1

Data readout

ANX1502 Details
Cold agglutinin disease

Phase 1a

Data readout

ANX005 (IV) Details
Warm autoimmune hemolytic anemia, Autoimmune disease

Failed

Discontinued