Compass Therapeutics, Inc., a clinical-stage oncology-focused biopharmaceutical company, engages in the development of antibody-based therapeutics for the treatment of various human diseases in the United States. The company's lead product candidates include tovecimig, a bispecific antibody that blocks Delta-like ligand 4 (DLL4) and vascular endothelial growth factor A (VEGF-A) signaling pathways, which are critical to angiogenesis and tumor vascularization; CTX-471, an IgG4 monoclonal antibody that is an agonist of CD137, a key co-stimulatory receptor on immune cells; and CTX-8371, a bispecific inhibitor that targets programmed cell death protein-1 (PD-1) and ligand PD-L1 checkpoint inhibitor antibodies. It also develops CTX-10726, a bispecific antibody that targets PD-1 and VEFG-A; and VEGF-IO Bispecific / Multiple, a bispecific antibody for angiogenesis pathway and anti-tumor immune that targets, including immune checkpoints, as well as analyzes VEGF combinations with other immune response-related proteins. Compass Therapeutics, Inc. was founded in 2014 and is headquartered in Boston, Massachusetts. Show more
80 Guest Street, Boston, MA, 02135, United States
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Market Cap
1.048B
52 Wk Range
$1.33 - $6.88
Previous Close
$5.89
Open
$5.93
Volume
2,005,852
Day Range
$5.84 - $6.01
Enterprise Value
504.3M
Cash
219.9M
Avg Qtr Burn
-10.85M
Insider Ownership
11.28%
Institutional Own.
88.17%
Qtr Updated
09/30/25
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| Drug & Indication | Stage & Event | Catalyst Date |
|---|---|---|
Tovecimig (CTX-009) (DLL4 and VEGF-A bispecific antibody) Details Biliary Tract Cancer | Phase 2/3 Data readout | |
Tovecimig (CTX-009) (DLL4 and VEGF-A bispecific antibody) Details Colorectal cancer | Phase 2 Initiation | |
CTX-471 +/- KEYTRUDA® (pembrolizumab) Details Cancer, Small cell lung cancer, Non-small cell lung carcinoma, Melanoma | Phase 2 Initiation | |
CTX-8371 Details Cancer, Solid tumor/s | Phase 1 Data readout | |
CTX-10726 (PD-1 x VEGF-A bispecific antibody) Details Solid tumor/s | IND Submission |
