CRIS - Curis

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Curis NasdaqCM:CRIS Curis, Inc., a biotechnology company, engages in the discovery and development of drug candidates for the treatment of human cancers in the United States. Its clinical stage drug candidates include Emavusertib, an oral small-molecule IRAK4 kinase inhibitor, which is in a Phase 1/2 open-label, single-arm expansion trial in patients with relapsed or refractory, or R/R, AML and high-risk myelodysplastic syndromes. The company's pipeline also includes Fimepinostat, an oral dual inhibitor of HDAC and PI3K enzymes for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma; CA-170, an oral, small-molecule antagonist designated as CA-170 that selectively targets PD-L1 and VISTA; and CA-327, an oral, small molecule, TIM3/PD-L1, which is a molecule antagonist of PD-L1 and TIM3. It has collaboration agreements with Genentech Inc., or Genentech and F. Hoffmann-La Roche Ltd, or Roche, for the commercialization of Erivedge, an orally-administered small molecule hedgehog signaling pathway antagonist for the treatment of advanced basal cell carcinoma, or BCC; Aurigene Discovery Technologies Limited for the discovery, development, and commercialization of small molecule compounds in the areas of immuno-oncology and precision oncology; and also licensed three programs under the Aurigene collaboration, including emavusertib. Curis, Inc. was incorporated in 2000 and is headquartered in Lexington, Massachusetts.

Location: Building C, Building C, Suite 500, Lexington, MA, 02421, United States | Website: https://www.curis.com | Industry: Biotechnology | Sector: Healthcare


Market Cap

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52 Wk Range

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Previous Close

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Avg Volume

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Enterprise Value

35.31M

Cash

20.28M

Avg Qtr Burn

-8.396M

Short % of Float

1.58%

Insider Ownership

8.64%

Institutional Own.

44.65%

Qtr Updated

03/31/25


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
Erivedge (vismodegib) Details
BCC (Basal Cell Carcinoma)

Approved

Quarterly sales

CA-4948 (emavusertib) Details
Acute myeloid leukemia, Myelodysplastic syndrome, Blood cancer, Cancer

Phase 1/2

Data readout

Phase 1/2

Update

CA-4948 (emavusertib)+/- ibrutinib Details
Blood cancer, Cancer, primary central nervous system lymphomas

Phase 1/2

Update

Phase 1

Data readout

Failed

Discontinued