CRIS - Curis

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Curis NASDAQ:CRIS Curis is a biotechnology company focused on the development of innovative therapeutics for the treatment of cancer. In 2015, Curis entered into a collaboration with Aurigene in the areas of immuno-oncology and precision oncology. As part of this collaboration, Curis has exclusive licenses to oral small molecule antagonists of immune checkpoints including the VISTA/PDL1 antagonist CA-170, and the TIM3/PDL1 antagonist CA-327, as well as the IRAK4 kinase inhibitor, CA-4948. CA-4948 is currently undergoing testing in a Phase 1 in patients with non-Hodgkin's lymphoma both as a monotherapy and in combination the with BTK inhibitor ibrutinib. Curis is also evaluating CA-4948 in a Phase 1 trial in patients with acute myeloid leukemia and myelodysplastic syndromes. In addition, Curis is engaged in a collaboration with ImmuNext for development of CI-8993, a monoclonal anti-VISTA antibody, which is currently undergoing testing in a Phase 1a/1b trial in patients with solid tumors. Curis is also party to a collaboration with Genentech, a member of the Roche Group, under which Genentech and Roche are commercializing Erivedge® for the treatment of advanced basal cell carcinoma.

Location: 128 Spring Street, Building C, Suite 500, Massachusetts, 02421, US | Website: www.curis.com | Industry: Biological Product (except Diagnostic) Manufacturing | Sector: Manufacturing


Market Cap

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52 Wk Range

$ - $

Previous Close

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Open

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Day Range

N/A - N/A

Volume

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Avg Volume

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Enterprise Value

46.14M

Cash

28.36M

Avg Qtr Burn

-10.68M

Short % of Float

2.46%

Insider Ownership

0.18%

Institutional Own.

38.75%

Qtr Updated

06/30/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
Erivedge (vismodegib) Details
BCC (Basal Cell Carcinoma)

Approved

Quarterly sales

CA-4948 (emavusertib) Details
Acute myeloid leukemia, Myelodysplastic syndrome, Blood cancer, Cancer

Phase 1/2

Data readout

CA-4948 (emavusertib)+/- ibrutinib Details
Blood cancer, Cancer, primary central nervous system lymphomas

Phase 1/2

Data readout

Phase 1/2

Initiation

Phase 1

Data readout