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Curis NASDAQ:CRIS Curis is a biotechnology company focused on the development of innovative therapeutics for the treatment of cancer. In 2015, Curis entered into a collaboration with Aurigene in the areas of immuno-oncology and precision oncology. As part of this collaboration, Curis has exclusive licenses to oral small molecule antagonists of immune checkpoints including the VISTA/PDL1 antagonist CA-170, and the TIM3/PDL1 antagonist CA-327, as well as the IRAK4 kinase inhibitor, CA-4948. CA-4948 is currently undergoing testing in a Phase 1 in patients with non-Hodgkin's lymphoma both as a monotherapy and in combination the with BTK inhibitor ibrutinib. Curis is also evaluating CA-4948 in a Phase 1 trial in patients with acute myeloid leukemia and myelodysplastic syndromes. In addition, Curis is engaged in a collaboration with ImmuNext for development of CI-8993, a monoclonal anti-VISTA antibody, which is currently undergoing testing in a Phase 1a/1b trial in patients with solid tumors. Curis is also party to a collaboration with Genentech, a member of the Roche Group, under which Genentech and Roche are commercializing Erivedge® for the treatment of advanced basal cell carcinoma.
Location: 128 Spring Street, Building C, Suite 500, Massachusetts, 02421, US | Website: www.curis.com | Industry: Biological Product (except Diagnostic) Manufacturing | Sector: Manufacturing
Market Cap
NaN
52 Wk Range
$ - $
Previous Close
$N/A
Open
$N/A
Day Range
N/A - N/A
Volume
N/A
Avg Volume
N/A
Enterprise Value
44.59M
Cash
28.36M
Avg Qtr Burn
-10.68M
Short % of Float
2.46%
Insider Ownership
0.18%
Institutional Own.
38.77%
Qtr Updated
06/30/24
Drug Pipeline
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Drug & Indication | Stage & Event | Catalyst Date |
---|---|---|
Erivedge (vismodegib) Details BCC (Basal Cell Carcinoma) | Approved Quarterly sales | |
CA-4948 (emavusertib)+/- ibrutinib Details Non-Hodgkin lymphoma, Blood cancer, Cancer | Phase 1/2 Data readout | |
CA-4948 (emavusertib) Details Acute myeloid leukemia, Myelodysplastic syndrome, Cancer, Blood cancer | Phase 1/2 Data readout | |
Phase 1/2 Initiation | ||
CI-8993 (anti-VISTA antibody) Details Solid tumor/s, Cancer | Phase 1 Data readout |