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Nurix Therapeutics NASDAQ:NRIX Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development, and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and other challenging diseases. Leveraging Nurix’s extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix’s drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels. Nurix’s wholly owned pipeline includes targeted protein degraders of Bruton’s tyrosine kinase, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene B, an E3 ligase that regulates T cell activation. Nurix is headquartered in San Francisco, California.

Location: | Website: www.nurixtx.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing

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52 Wk Range

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Enterprise Value

1.183B

Cash

443.1M

Avg Qtr Burn

-24.03M

Short % of Float

18.20%

Insider Ownership

1.87%

Institutional Own.

Qtr Updated

05/31/24

Drug Pipeline

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Drug & Indication	Stage & Event	Catalyst Date
NX-1607 Details Cancer, Solid tumor/s	Phase 1 Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
NX-2127 (BTK degrader) Details Chronic lymphocytic leukemia, Blood cancer, Cancer, B-cell malignancies, Non-Hodgkin lymphoma, Diffuse large B cell lymphoma, Mantle cell lymphoma	Phase 1 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
NX-5948 Details Cancer, B-cell malignancies	Phase 1 Update	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
NX-1607 + paclitaxel Details Solid tumor/s, Cancer	Phase 1a Data readout	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.
DeTIL-0255 Details Ovarian cancer, Cancer, Cervical cancer, Endometrial cancer	Failed Discontinued	Some catalyst date You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details. You must sign up to see the catalyst details.Sign up now.