ONCS - OncoSec Medical

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OncoSec Medical NASDAQ:ONCS OncoSec Medical Incorporated is a late-stage biotechnology company focused on developing cytokine-based intratumoral immunotherapies to stimulate the body's immune system to target and attack cancer. OncoSec's lead immunotherapy investigational product candidate - TAVO™ (tavokinogene telseplasmid) - enables the intratumoral delivery of DNA-based interleukin-12 (IL-12), a naturally occurring protein with immune-stimulating functions. The technology, which employs electroporation, is designed to produce a controlled, localized expression of IL-12 in the tumor microenvironment, enabling the immune system to target and attack tumors throughout the body. OncoSec has built a deep and diverse clinical pipeline utilizing TAVO™ as a potential treatment for multiple cancer indications either as a monotherapy or in combination with leading checkpoint inhibitors; with the latter potentially enabling OncoSec to address a great unmet medical need in oncology: anti-PD-1 non-responders. Results from recently completed clinical studies of TAVO™ have demonstrated a local immune response, and subsequently, a systemic effect as either a monotherapy or combination treatment approach along with an acceptable safety profile, warranting further development. In addition to TAVO™, OncoSec is identifying and developing new DNA-encoded therapeutic candidates and tumor indications for use with its new Visceral Lesion Applicator (VLA), to target deep visceral lesions, such as liver, lung or pancreatic lesions.

Location: 24 N Main St, New Jersey, 08534-2218, US | Website: www.oncosec.com | Industry: Pharmaceutical Preparation Manufacturing | Sector: Manufacturing


Market Cap

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52 Wk Range

$ - $

Previous Close

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Day Range

N/A - N/A

Volume

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Avg Volume

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Enterprise Value

0.00

Cash

148.3M

Avg Qtr Burn

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Short % of Float

8.22%

Insider Ownership

28.01%

Institutional Own.

5.83%

Qtr Updated

06/30/24


Drug Pipeline

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Drug & IndicationStage & EventCatalyst Date
TAVO™-EP + OPDIVO® (nivolumab) Details
Melanoma, Prostate cancer, Cancer

Phase 2

Data readout

TAVO™-EP + pembrolizumab Details
Melanoma, Rhabdomyosarcoma, Thermal burns, Non-small cell lung carcinoma, Cancer

Phase 2

Update

CORVax12 (TAVO + SARS-CoV-2 spike glycoprotein) Details
COVID-19, Hepatitis B vaccine, Hepatitis B

Failed

Discontinued

TAVO™-EP + epacadostat + pembrolizumab Details
Cancer, Head and neck cancer, Head and neck squamous cell carcinoma

Failed

Discontinued

TAVO™-EP + pembrolizumab Details
Breast cancer, Triple-negative breast cancer

Failed

Discontinued