Oncternal Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development of oncology therapies for cancers with critical unmet medical needs. The company's clinical pipeline includes zilovertamab, a humanized monoclonal antibody that binds to receptor-tyrosine kinase-like Orphan Receptor 1 (ROR1); and ONCT-216, a small molecule inhibiting the biological activity of ETS-family transcription factor oncoproteins, which is in Phase 1/2 clinical trial. It is also developing ONCT-808, a chimeric antigen receptor T-cells (CAR-T), which is in Phase 1/2 clinical trial for the treatment of hematologic malignancies and solid tumors, as well as targets ROR1; and ONCT-534, a dual-action androgen receptor inhibitor product candidate in preclinical development for the treatment of castration-resistant prostate and other androgen receptor-driven cancers. The company has license agreements with the Regents of the University of California; Georgetown University; The University of Texas MD Anderson Cancer Center; Shanghai Pharmaceutical (USA) Inc.; and University of Tennessee Research Foundation. Oncternal Therapeutics, Inc. is headquartered in San Diego, California. Show more

12230 El Camino Real, San Diego, CA, 92130, United States

Biotechnology
Healthcare
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Market Cap

0.00

52 Wk Range

$N/A - $N/A

Previous Close

$0.53

Open

$0.53

Volume

N/A

Day Range

$0.53 - $0.53

Enterprise Value

0.00

Cash

0.00

Avg Qtr Burn

N/A

Insider Ownership

9.23%

Institutional Own.

12.07%

Qtr Updated

09/30/24


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Drug & IndicationStage & EventCatalyst Date
ONCT-808 (CAR-T) Details
Hematologic malignancies, Cancer, B-cell lymphoma

Phase 1/2

Data readout

ONCT-534 Details
Cancer, Castration-resistant prostate cancer

Failed

Discontinued

Failed

Discontinued

Zilovertamab (Cirmtuzumab) (ROR1) + Ibrutinib Details
Blood cancer, Chronic lymphocytic leukemia, Cancer, Mantle cell lymphoma

Failed

Discontinued

Zilovertamab (Cirmtuzumab) (ROR1) + Ibrutinib Details
Blood cancer, Cancer, Mantle cell lymphoma

Failed

Discontinued

ONCT-216 (TK216) (EWS-FLI1 inhibitor) Details
Relapsed/refractory Ewing sarcoma, Cancer

Failed

Discontinued